Maciolek Lynsey M, Harmon Taylor S, He Jing, Sadruddin Sarfaraz, Nguyen Quan D
Radiology, University of Texas Medical Branch, Galveston, USA.
Radiology, University of Florida College of Medicine, Jacksonville, USA.
Cureus. 2019 Jun 17;11(6):e4923. doi: 10.7759/cureus.4923.
Pseudoangiomatous stromal hyperplasia (PASH) in male patients is a rare condition that represents a hormonally-induced proliferation of mesenchymal tissue of the breast. This benign pathology is often undiagnosed due to many reasons. When PASH presents as a breast mass, it appears innocent, developing as a smooth and well-circumscribed tumor. Furthermore, it does not elicit suspicious findings on imaging. These points often halt further investigation of many breast abnormalities. Breast masses are statistically most likely to be gynecomastia when they arise in men. However, they are important to investigate because, although rare, breast cancer can occur in men. Furthermore, the benign conditions of the breast that commonly affect women can also impact male patients. It is oftentimes overlooked that men too can experience hormonal stimulation of the breast tissue. The following case describes this rare but important instance of a male patient diagnosed with PASH following a previous diagnosis of infiltrative ductal carcinoma in situ of the contralateral breast.
男性患者的假性血管瘤样间质增生（PASH）是一种罕见病症，表现为乳腺间叶组织的激素诱导性增生。由于多种原因，这种良性病变常常未被诊断出来。当PASH表现为乳腺肿块时，它看似无害，呈光滑且边界清晰的肿瘤状生长。此外，它在影像学上不会引发可疑表现。这些情况常常使对许多乳腺异常的进一步检查停滞不前。从统计学角度来看，男性出现乳腺肿块时最有可能是男性乳腺增生。然而，对其进行检查很重要，因为尽管罕见，但男性也可能患乳腺癌。此外，通常影响女性的乳腺良性疾病也会对男性患者产生影响。人们常常忽略男性也会经历乳腺组织的激素刺激。以下病例描述了这样一个罕见但重要的情况：一名男性患者在之前被诊断为对侧乳腺原位浸润性导管癌后，又被诊断出患有PASH。
