• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Adjuvant chemotherapy for node negative, high Recurrence Score breast cancer: in defense of de-escalation.淋巴结阴性、复发评分高的乳腺癌辅助化疗:支持降阶梯治疗
NPJ Breast Cancer. 2019 Aug 12;5:24. doi: 10.1038/s41523-019-0119-5. eCollection 2019.
2
Impact of oncotype DX recurrence score in the management of breast cancer cases.Oncotype DX 复发评分对乳腺癌病例管理的影响。
Clin Breast Cancer. 2014 Jun;14(3):182-90. doi: 10.1016/j.clbc.2013.12.002. Epub 2013 Dec 27.
3
Therapeutic escalation - De-escalation: Data from 15.508 early breast cancer treated with upfront surgery and sentinel lymph node biopsy (SLNB).治疗升级 - 降级:来自15508例接受 upfront 手术和前哨淋巴结活检(SLNB)治疗的早期乳腺癌患者的数据。 (注:“upfront”在这里可能是“初次、 upfront”等不太准确的表述,结合语境更准确的可能是“初始”之类的意思,但按照要求不添加解释。)
Breast. 2017 Aug;34:24-33. doi: 10.1016/j.breast.2017.04.008. Epub 2017 May 3.
4
Impact of Oncotype DX breast Recurrence Score testing on adjuvant chemotherapy use in early breast cancer: Real world experience in Greater Manchester, UK.Oncotype DX乳腺复发评分检测对早期乳腺癌辅助化疗使用的影响:英国大曼彻斯特地区的真实世界经验
Eur J Surg Oncol. 2017 May;43(5):931-937. doi: 10.1016/j.ejso.2016.12.010. Epub 2017 Jan 9.
5
Impact of the 21-gene recurrence score assay compared with standard clinicopathologic guidelines in adjuvant therapy selection for node-negative, estrogen receptor-positive breast cancer.21 基因复发评分检测对淋巴结阴性、雌激素受体阳性乳腺癌辅助治疗选择中标准临床病理指南的影响。
Ann Surg Oncol. 2011 Nov;18(12):3399-406. doi: 10.1245/s10434-011-1698-z. Epub 2011 May 3.
6
Neo-adjuvant chemotherapy and axillary de-escalation management for patients with clinically node-negative breast cancer.新辅助化疗和临床淋巴结阴性乳腺癌的腋窝降阶管理。
Breast J. 2019 Nov;25(6):1154-1159. doi: 10.1111/tbj.13422. Epub 2019 Jul 22.
7
Real-World Outcomes of Adjuvant Chemotherapy for Node-Negative and Node-Positive HER2-Positive Breast Cancer.辅助化疗治疗淋巴结阴性和淋巴结阳性 HER2 阳性乳腺癌的真实世界结局。
J Natl Compr Canc Netw. 2019 Jan;17(1):47-56. doi: 10.6004/jnccn.2018.7066.
8
Prospective Evaluation of the Impact of the 21-Gene Recurrence Score Assay on Adjuvant Treatment Decisions for Women with Node-Positive Breast Cancer in Ontario, Canada.加拿大安大略省淋巴结阳性乳腺癌女性患者 21 基因复发评分检测对辅助治疗决策影响的前瞻性评估
Oncologist. 2018 Jul;23(7):768-775. doi: 10.1634/theoncologist.2017-0346. Epub 2018 Jan 25.
9
Adjuvant therapy of node-negative breast cancer.淋巴结阴性乳腺癌的辅助治疗
Ann Pharmacother. 1995 Mar;29(3):289-98. doi: 10.1177/106002809502900311.
10
[Effect of 21-gene recurrence score on chemotherapy decisions for patients with estrogen receptor-positive, epidermal growth factor receptor 2-negative and lymph node-negative early stage-breast cancer].21基因复发评分对雌激素受体阳性、表皮生长因子受体2阴性且淋巴结阴性的早期乳腺癌患者化疗决策的影响
Zhonghua Zhong Liu Za Zhi. 2017 Jul 23;39(7):502-508. doi: 10.3760/cma.j.issn.0253-3766.2017.07.005.

本文引用的文献

1
Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26 randomised trials.增加化疗剂量强度:通过更频繁的给药或序贯方案在 26 项随机试验中 37 298 例早期乳腺癌患者的个体水平荟萃分析。
Lancet. 2019 Apr 6;393(10179):1440-1452. doi: 10.1016/S0140-6736(18)33137-4. Epub 2019 Feb 8.
2
'Nudging' Surgeons and Patients to De-Escalation of Surgery for Breast Cancer.引导外科医生和患者减少乳腺癌手术规模
Ann Surg Oncol. 2018 Oct;25(10):2777-2780. doi: 10.1245/s10434-018-6588-1. Epub 2018 Jul 2.
3
Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer.基于 21 基因表达检测的乳腺癌辅助化疗。
N Engl J Med. 2018 Jul 12;379(2):111-121. doi: 10.1056/NEJMoa1804710. Epub 2018 Jun 3.
4
De-escalation of breast radiotherapy after conserving surgery in low-risk early breast cancer patients.保乳手术后低危早期乳腺癌患者的放疗降阶。
Med Oncol. 2018 Apr 3;35(5):62. doi: 10.1007/s12032-018-1121-8.
5
Acute myeloid leukemia and myelodysplastic syndrome after adjuvant chemotherapy: A population-based study among older breast cancer patients.辅助化疗后急性髓系白血病和骨髓增生异常综合征:老年乳腺癌患者的一项基于人群的研究。
Cancer. 2018 Mar 1;124(5):899-906. doi: 10.1002/cncr.31144. Epub 2017 Dec 13.
6
21-Gene Recurrence Score for prognosis and prediction of taxane benefit after adjuvant chemotherapy plus endocrine therapy: results from NSABP B-28/NRG Oncology.21 基因复发评分用于辅助化疗加内分泌治疗后的预后和紫杉烷获益预测:来自 NSABP B-28/NRG 肿瘤学的结果。
Breast Cancer Res Treat. 2018 Feb;168(1):69-77. doi: 10.1007/s10549-017-4550-8. Epub 2017 Nov 11.
7
Long-term Peripheral Neuropathy in Breast Cancer Patients Treated With Adjuvant Chemotherapy: NRG Oncology/NSABP B-30.接受辅助化疗的乳腺癌患者的长期周围神经病变:NRG肿瘤学/NSABP B-30研究。
J Natl Cancer Inst. 2018 Feb 1;110(2). doi: 10.1093/jnci/djx162.
8
De-escalating and escalating systemic therapy in triple negative breast cancer.三阴性乳腺癌的降阶梯和升阶梯全身治疗。
Breast. 2017 Aug;34 Suppl 1:S112-S115. doi: 10.1016/j.breast.2017.06.041. Epub 2017 Jul 8.
9
De-Escalation Strategies in Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Early Breast Cancer (BC): Final Analysis of the West German Study Group Adjuvant Dynamic Marker-Adjusted Personalized Therapy Trial Optimizing Risk Assessment and Therapy Response Prediction in Early BC HER2- and Hormone Receptor-Positive Phase II Randomized Trial-Efficacy, Safety, and Predictive Markers for 12 Weeks of Neoadjuvant Trastuzumab Emtansine With or Without Endocrine Therapy (ET) Versus Trastuzumab Plus ET.人表皮生长因子受体 2(HER2)阳性早期乳腺癌(BC)的降级策略:德国西部研究组辅助动态标志物调整个体化治疗试验的最终分析,该试验优化了早期 BC 的 HER2 和激素受体阳性患者的风险评估和治疗反应预测,随机 II 期试验比较了曲妥珠单抗恩坦辛联合或不联合内分泌治疗(ET)与曲妥珠单抗加 ET 的新辅助治疗 12 周的疗效、安全性和预测标志物。
J Clin Oncol. 2017 Sep 10;35(26):3046-3054. doi: 10.1200/JCO.2016.71.9815. Epub 2017 Jul 6.
10
Trial designs and results supporting treatment de-escalation and escalation.支持治疗降级和升级的试验设计和结果。
Breast. 2017 Aug;34 Suppl 1:S10-S12. doi: 10.1016/j.breast.2017.06.020. Epub 2017 Jun 30.

Adjuvant chemotherapy for node negative, high Recurrence Score breast cancer: in defense of de-escalation.

作者信息

Lake Diana, Seidman Andrew D

机构信息

Breast Medicine Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY USA.

出版信息

NPJ Breast Cancer. 2019 Aug 12;5:24. doi: 10.1038/s41523-019-0119-5. eCollection 2019.

DOI:10.1038/s41523-019-0119-5
PMID:31428677
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6690957/
Abstract
摘要