Internal Medicine Service, General University Hospital of Alicante, Calle Pintor Baeza 12, 03010, Alicante, Spain.
Infectious Diseases Unit, General University Hospital of Alicante, Calle Pintor Baeza 12, 03010, Alicante, Spain.
Aging Clin Exp Res. 2020 Jul;32(7):1383-1388. doi: 10.1007/s40520-019-01314-3. Epub 2019 Aug 19.
To compare the clinical and epidemiological characteristics and the evolution of infective endocarditis in adults aged under 65 years, 65-79 years, and 80 years or older.
An observational retrospective cohort study in patients with infective endocarditis was performed in a public hospital in Spain from January 2013 to December 2017.
Seventy-two patients were treated: 26 (36.1%) were under 65 years old, 28 (38.9%) were 65-79 years old, and 18 (25%) were aged 80 or older. Prosthetic valve endocarditis was less common in patients aged 65-79 years (3.6%) than in younger (23.1%; p = 0.047) or older (38.9%; p = 0.004) patients. In contrast, degenerative heart disease was more prevalent in the 65-79 year age group [64.3% compared to 15.4% (p < 0.001) in the youngest group, and 33.3% (p = 0.04) in the oldest]. Surgical interventions were similar in patients aged 65-79 (50%) and under 65 years (42.3%), but less common in people over 80 years (16.7%; p = 0.022).
The characteristics of infective endocarditis are different in patients aged 65-79 years and in those over 80 years.
比较 65 岁以下、65-79 岁和 80 岁及以上成年人感染性心内膜炎的临床和流行病学特征及演变过程。
本研究为西班牙一家公立医院开展的观察性回顾性队列研究，纳入了 2013 年 1 月至 2017 年 12 月期间的感染性心内膜炎患者。
共纳入 72 例患者：26 例（36.1%）年龄<65 岁，28 例（38.9%）年龄 65-79 岁，18 例（25%）年龄≥80 岁。与年轻患者（23.1%；p=0.047）或老年患者（38.9%；p=0.004）相比，65-79 岁患者中人工瓣膜心内膜炎较少见（3.6%）。相反，退行性心脏病在 65-79 岁年龄组中更为常见[64.3%比最年轻组的 15.4%（p<0.001）和最年长组的 33.3%（p=0.04）]。65-79 岁和<65 岁患者的手术干预相似（分别为 50%和 42.3%），但 80 岁以上患者的手术干预较少（16.7%；p=0.022）。
65-79 岁和 80 岁以上患者的感染性心内膜炎特征不同。
