Chirchiglia Domenico, Chirchiglia Pasquale, Stroscio Carmelino, Volpentesta Giorgio, Lavano Angelo
Department of Neurosurgery, University of Catanzaro, Catanzaro, Italy.
J Neurol Surg A Cent Eur Neurosurg. 2019 Nov;80(6):503-506. doi: 10.1055/s-0039-1685197. Epub 2019 Aug 20.
Oxygen-ozone therapy is used to treat degenerative pathology of the spine when surgery is not needed (e.g., removal of a herniated disk). Some authors have described it as a safe and effective procedure in ∼ 70 to 90% of patients. The aim of the therapy is to dehydrate the intervertebral disk and alter its contents. However, this treatment has been associated with some rare but very serious side effects. Both cardiac damage and a case of fulminant septicemia were reported. We describe a case of suspected pulmonary embolism, followed by sudden death, in an elderly woman treated with oxygen-ozone therapy for lumbar pain caused by disk protrusion. We believe a massive pulmonary embolism occurred, probably caused by an intradiskal injection that accidentally punctured a venous vessel and created emboli.
当不需要进行手术（如摘除椎间盘突出）时，氧-臭氧疗法可用于治疗脊柱退行性病变。一些作者称，该疗法在约70%至90%的患者中是安全有效的。该疗法的目的是使椎间盘脱水并改变其内容物。然而，这种治疗方法也伴随着一些罕见但非常严重的副作用。曾有心脏损伤和一例暴发性败血症的报道。我们描述了一例接受氧-臭氧疗法治疗因椎间盘突出引起的腰痛的老年女性，她先是疑似发生肺栓塞，随后猝死。我们认为发生了大面积肺栓塞，可能是由于椎间盘内注射意外刺破静脉血管并形成栓子所致。
