Department of Psychological Sciences, University of Connecticut, 406 Babbidge Rd, U-1020, Storrs, CT, 06269-1020, USA.
Mercer University School of Medicine, Macon, GA, USA.
AIDS Behav. 2020 Jan;24(1):185-191. doi: 10.1007/s10461-019-02644-z.
Although anticipated HIV-related stigma-the expectation that one will experience prejudice and discrimination in the future as a result of others learning his or her HIV positive status-is theorized to be a robust predictor of antiretroviral therapy (ART) non-adherence, the association between anticipated stigma and ART non-adherence has been inconsistent. It may be, however, that anticipated stigma reliably, but indirectly, contributes to poor ART adherence through other psychosocial mechanisms. In the current study, we examine whether anticipated stigma indirectly contributes to treatment non-adherence through increased medication concerns. In a cross-sectional study, 585 people living with HIV in Atlanta and Macon, Georgia completed measures of anticipated HIV-related stigma, HIV-medication concerns, and HIV-treatment adherence. A latent variable mediation analysis revealed that anticipated stigma was positively associated with increased medication concerns, which consequently contributed to treatment non-adherence. Results reveal a psychosocial mechanism by which anticipated stigma contributes to ART non-adherence.
尽管预期的 HIV 相关耻辱感（即他人得知其 HIV 阳性身份后，预计将来会遭受偏见和歧视）被理论上认为是抗逆转录病毒疗法 (ART) 不依从的有力预测因素，但预期耻辱感与 ART 不依从之间的关联并不一致。然而，可能是预期的耻辱感通过其他心理社会机制可靠地但间接地导致 ART 依从性差。在当前的研究中，我们研究了预期的耻辱感是否通过增加药物顾虑来间接地导致治疗不依从。在一项横断面研究中，佐治亚州亚特兰大和梅肯的 585 名 HIV 感染者完成了预期的 HIV 相关耻辱感、HIV 药物顾虑和 HIV 治疗依从性的测量。潜变量中介分析显示，预期的耻辱感与增加的药物顾虑呈正相关，而这些顾虑又导致治疗不依从。研究结果揭示了预期耻辱感导致 ART 不依从的心理社会机制。
