基于感知和无感知脊髓刺激器联合治疗全膝关节置换术后持续性疼痛的病例研究

A Case Study of Combined Perception-Based and Perception-Free Spinal Cord Stimulator Therapy for the Management of Persistent Pain after a Total Knee Arthroplasty.

作者信息

Urits Ivan, Osman Mohamed, Orhurhu Vwaire, Viswanath Omar, Kaye Alan D, Simopoulos Thomas, Yazdi Cyrus

机构信息

Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Valley Anesthesiology and Pain Consultants, Envision Physician Services, Phoenix, AZ, USA.

出版信息

Pain Ther. 2019 Dec;8(2):281-284. doi: 10.1007/s40122-019-00136-5. Epub 2019 Aug 20.

Abstract

INTRODUCTION

Total knee arthroplasty (TKA) is an effective treatment modality for severe osteoarthritis of the knee. Causes of pain following TKA are poorly understood; however, patient-specific biology and various neuropathic underlying mechanisms such as neuroma formation and complex regional pain syndrome (CRPS) have been suggested. Our case demonstrated the successful treatment of CRPS in the knee with the use of combination therapy in spinal cord stimulator.

CASE

We present a 71-year-old Caucasian non-Hispanic male who presented with chronic left knee pain after undergoing a total knee arthroplasty (TKA) 18 months prior. Following his TKA, he reported doing well in the acute post-operative period but began to develop progressively worsening left knee pain at approximately the third post-operative week. He underwent a successful spinal cord stimulator (SCS) trial and subsequent implantation of two 16-contact Boston Scientific leads with a Boston Scientific Spectra WaveWriterTM SCS system. Upon first post-procedural follow-up, and moreover at his 6-month follow-up, the patient reported complete resolution of his symptoms.

DISCUSSION

The development of persistent pain following TKA is a significant complication that is often challenging to treat. Our case demonstrated the successful treatment of CRPS in the knee with the use of combination therapy in spinal cord stimulator therapy. We anticipate that more data will continue to emerge to assess for the safety and efficacy of combination therapy.

摘要

引言

全膝关节置换术(TKA)是治疗重度膝关节骨关节炎的有效方法。TKA术后疼痛的原因尚不清楚;然而,已有人提出特定患者的生物学因素以及各种神经病理性潜在机制,如神经瘤形成和复杂性区域疼痛综合征(CRPS)。我们的病例展示了通过脊髓刺激器联合治疗成功治愈膝关节CRPS。

病例

我们报告一名71岁的非西班牙裔白人男性,他在18个月前接受了全膝关节置换术(TKA)后出现慢性左膝疼痛。TKA术后,他报告在术后急性期恢复良好,但在术后约第三周开始逐渐出现左膝疼痛加重。他成功进行了脊髓刺激器(SCS)试验,并随后植入了两根带有波士顿科学Spectra WaveWriterTM SCS系统的16触点波士顿科学导联。在首次术后随访以及6个月随访时,患者报告症状完全缓解。

讨论

TKA术后持续疼痛的发生是一种严重并发症,通常治疗具有挑战性。我们的病例展示了通过脊髓刺激器联合治疗成功治愈膝关节CRPS。我们预计将有更多数据不断涌现,以评估联合治疗的安全性和有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e080/6857201/68dd9573bab9/40122_2019_136_Fig1_HTML.jpg

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