Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Department of Oncology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
J Knee Surg. 2021 Feb;34(3):247-250. doi: 10.1055/s-0039-1694736. Epub 2019 Aug 21.
Diffuse-type pigmented villonodular synovitis is a rare benign disease that causes disorders of the knee, including erosion of subchondral bone and cyst formation, with eventual osteoarthritis. The purpose of this study was to evaluate the short-term outcomes of synovectomy and total knee replacement in patients with the diffuse type of pigmented villonodular synovitis. From November 2011 to May 2015, we performed synovectomy and total knee replacement in 28 patients with diffuse pigmented villonodular synovitis diagnosed on the basis of histopathology of biopsy specimens. Clinical data were collected perioperatively and during follow-up for evaluation of surgical efficacy. No intraoperative complications were encountered. Mean operative duration was 73.4 minutes (range: 47-115 minutes); mean estimated blood loss was 223.9 mL (range: 50-600 mL). The mean duration of follow-up was 58.7 months (range: 36-84 months). Mean range of motion improved from 86.1 ± 11.3 degrees (range: 60-100 degrees) to 107 ± 11.4 degrees (range: 90-130 degrees). Average Knee Society clinical scores improved from 38.9 ± 9.5 (range: 17-54) to 84.4 ± 6.1 (range: 75-98); functional scores improved from 48.9 ± 13.1 (range: 25-80) to 84.6 ± 6.1 (range: 75-95; < 0.05 for both). Postoperative radiographs showed no signs of prosthesis loosening, periprosthetic fractures, or dislocation. The short-term efficacy of synovectomy and total knee replacement in treating patients with diffuse pigmented villonodular synovitis was satisfactory.
弥漫型色素绒毛结节性滑膜炎是一种罕见的良性疾病，可引起膝关节紊乱，包括软骨下骨侵蚀和囊肿形成，最终导致骨关节炎。本研究旨在评估弥漫型色素绒毛结节性滑膜炎患者行滑膜切除术和全膝关节置换术的短期疗效。2011 年 11 月至 2015 年 5 月，我们对 28 例经组织病理学活检诊断为弥漫型色素绒毛结节性滑膜炎的患者进行了滑膜切除术和全膝关节置换术。收集围手术期和随访期间的临床资料，评估手术疗效。术中无并发症发生。平均手术时间为 73.4 分钟（47-115 分钟）；平均估计失血量为 223.9 毫升（50-600 毫升）。平均随访时间为 58.7 个月（36-84 个月）。平均关节活动度从 86.1±11.3 度（60-100 度）改善至 107±11.4 度（90-130 度）。膝关节学会临床评分从 38.9±9.5（17-54）平均提高至 84.4±6.1（75-98）；功能评分从 48.9±13.1（25-80）平均提高至 84.6±6.1（75-95）；（均<0.05）。术后 X 线片未见假体松动、假体周围骨折或脱位。滑膜切除术和全膝关节置换术治疗弥漫型色素绒毛结节性滑膜炎的短期疗效满意。
