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[采用单一切口行根治性外阴切除术及腹股沟淋巴结清扫术治疗外阴恶性肿瘤]

[Radical vulvectomy and inguinal lymphadenectomy using a single incision for the treatment of vulvar malignancy].

作者信息

Wang Y F, Chen G W, Ma Y, Zheng Y H, He L Q, He W Q, Dai G Y, Zhou Y F, Chen Y Y, Liu M J, Feng W Q

机构信息

Department of Obstetrics and Gynecology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2019 Aug 20;99(31):2450-2454. doi: 10.3760/cma.j.issn.0376-2491.2019.31.009.

Abstract

To describe a novel procedure of radical vulvectomy and inguinal lymphadenectomy using a single incision (RVIL-SI) for the treatment of vulvar malignancy. In March, 2019, two cases affected with vulvar cancer (the first one is stage ⅢA squamous cell carcinoma and the second one is stage ⅠB with malignant melanoma) underwent this novel procedure, which was characterized by the combination of radical vulvectomy and bilateral inguinal lymphadenectomy without making additional incisions in groin areas. The boundaries of femoral triangle could be exposed perfectly using the initial incision of radical vulvectomy and the combined superficial and deep groin lymph node dissection were done subcutaneously from medial to lateral. Preoperative data and short term follow-up outcomes were collected. The RVIL-SI was successfully conducted in two patients without any incisions of groin. The great saphenous veins were all spared. The operative time, average blood loss and median total regional lymph nodes of two cases were close. No major intraoperative complications occurred. Micrometastasis in one right superficial inguinal node was found in the first case with ipsilateral huge cancer lesion. No drain tube was left in inguinal areas intraoperatively. On postoperative day 3, the second case suffered mild lymphocele of right groin, which was resolved via repeated percutaneous needle puncture followed by elastic compression. Postoperative hospital stay of two cases were 10 and 11 days, respectively. With no skin complication at the time of writing this report. Our preliminary experience with the RVIL-SI has confirmed the reproducibility and minimal invasive therapeutic potential in the treatment for patients with vulvar cancer. But this novel procedure is in its infancy stage. Although short-term results are encouraging, a larger series with longer follow-up are required to fully evaluate the therapeutic efficacy.

摘要

描述一种采用单一切口进行根治性外阴切除术和腹股沟淋巴结清扫术(RVIL-SI)治疗外阴恶性肿瘤的新方法。2019年3月,两名外阴癌患者(第一例为ⅢA期鳞状细胞癌,第二例为ⅠB期恶性黑色素瘤)接受了这一新方法治疗,其特点是在不额外切开腹股沟区域的情况下,将根治性外阴切除术和双侧腹股沟淋巴结清扫术相结合。利用根治性外阴切除术的初始切口可完美暴露股三角边界,并从内侧向外侧在皮下进行腹股沟浅深淋巴结联合清扫。收集术前数据和短期随访结果。两名患者均成功实施了RVIL-SI,腹股沟无额外切口。大隐静脉均得以保留。两例患者的手术时间、平均失血量和区域淋巴结总数中位数相近。术中未发生重大并发症。第一例同侧有巨大癌灶的患者,右侧腹股沟浅淋巴结发现微小转移。术中腹股沟区未留置引流管。术后第3天,第二例患者右侧腹股沟出现轻度淋巴囊肿,经反复经皮穿刺并弹力压迫后消退。两例患者术后住院时间分别为10天和11天。撰写本报告时无皮肤并发症。我们对RVIL-SI的初步经验证实了其在治疗外阴癌患者中的可重复性和微创治疗潜力。但这一新方法尚处于起步阶段。尽管短期结果令人鼓舞,但仍需要更大规模的系列研究和更长时间的随访来全面评估其治疗效果。

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