Hacker N F, Leuchter R S, Berek J S, Castaldo T W, Lagasse L D
Obstet Gynecol. 1981 Nov;58(5):574-9.
One hundred patients underwent radical vulvectomy and bilateral inguinal lymphadenectomy using separate groin incisions. Forty-nine had stage I disease, 37 stage II, and 14 stage III. Corrected actuarial 5-year survival for each stage was 97.4, 86, and 49.2%, respectively. Inguinal lymph nodes were positive in 25% of cases: 10.2% of stage I, 27% of stage II, and 71.4% of stage III cases. Major complications occurred in 21 patients, including major groin breakdown in 14. Thirty patients experienced no acute postoperative morbidity. The mean postoperative hospital stay was 19 days, and mean operative blood loss was 620 ml. No patients developed isolated metastases in either the groin or the inguinal skin bridge, but 2 stage III patients developed simultaneous metastases in the skin bridge and elsewhere. For appropriately selected patients, separate groin incisions for inguinal lymphadenectomy appear to result in lower morbidity than traditional methods, without compromising survival.
100例患者接受了根治性外阴切除术及双侧腹股沟淋巴结清扫术，腹股沟切口分开。49例为Ⅰ期疾病，37例为Ⅱ期，14例为Ⅲ期。各期校正后的精算5年生存率分别为97.4%、86%和49.2%。25%的病例腹股沟淋巴结阳性：Ⅰ期为10.2%，Ⅱ期为27%，Ⅲ期为71.4%。21例患者发生了主要并发症，其中14例出现严重腹股沟破溃。30例患者术后无急性发病情况。术后平均住院时间为19天，平均手术失血量为620毫升。没有患者在腹股沟或腹股沟皮桥单独出现转移，但2例Ⅲ期患者在皮桥及其他部位同时出现转移。对于选择合适的患者，腹股沟淋巴结清扫术采用分开的腹股沟切口似乎比传统方法导致的发病率更低，且不影响生存率。
