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遗传造血克隆亚型的合并症和炎症特征。

Comorbid and inflammatory characteristics of genetic subtypes of clonal hematopoiesis.

机构信息

Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada.

Baycrest Health Sciences, Toronto, ON, Canada.

出版信息

Blood Adv. 2019 Aug 27;3(16):2482-2486. doi: 10.1182/bloodadvances.2018024729.

DOI:10.1182/bloodadvances.2018024729
PMID:31434682
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6712533/
Abstract

CH may be associated with broader ill health (worse performance status, increased and potentially novel comorbidities). Serum interleukin-6 is elevated in people with CH and genetic subtypes, providing a view of the human systemic inflammatory landscape of CH.

摘要

充血性心力衰竭可能与更广泛的健康不良(较差的表现状态、增加和潜在的新合并症)有关。患有充血性心力衰竭和遗传亚型的人的血清白细胞介素-6升高,提供了充血性心力衰竭的人类全身炎症景观的观点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8248/6712533/44c3ed73966d/advances024729absf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8248/6712533/44c3ed73966d/advances024729absf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8248/6712533/44c3ed73966d/advances024729absf1.jpg

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