Marcinkiewicz M, Linard C G, Seidah N G, Chrétien M
Laboratories J. A. de Sève de Neuroendocrinologie moléculaire, Institut de Recherches cliniques de Montréal, Québec, Canada.
C R Acad Sci III. 1988;307(12):689-94.
Immunoreactivity to the secretory protein 7B2 (IR-7B2) colocalizes with both AVP and Om in separate groups of neurons in the supraoptic nucleus. In mutant Brattleboro rats, which have aberrant AVP, which results in diabetes insipidus, 7B2 appears to be markedly decreased in vasopressinergic neurons and absent in their corresponding neurohypophyseal terminals. In contrast, no dramatic differences could be observed in oxytonergic somatas and fibers.
对分泌蛋白7B2的免疫反应性（IR-7B2）与视上核中不同组神经元中的抗利尿激素（AVP）和催产素（Om）均共定位。在患有异常AVP并导致尿崩症的突变型布拉特洛维大鼠中，7B2在加压素能神经元中似乎明显减少，并且在其相应的神经垂体终末中不存在。相比之下，在催产素能胞体和纤维中未观察到明显差异。
