Department of Cardiovascular Medicine, Section of Cardiac Electrophysiology and Pacing, Cleveland Clinic, 9500 Euclid Avenue, J2-2, Cleveland, OH, 44195, USA.
Clin Auton Res. 2020 Feb;30(1):79-83. doi: 10.1007/s10286-019-00633-9. Epub 2019 Aug 21.
Prior studies have reported ECG (Electrocardiogram) changes during tilt table testing (TTT), specifically during repolarization with ST-segment and T-wave changes. The correlation with ischemic evaluation remains unclear. The purpose of this study was to analyze the prevalence of ST-segment changes during TTT in a young, otherwise healthy population of patients with postural tachycardia syndrome (POTS), and correlate them with exercise stress test results.
Two hundred and fifty-five patients with POTS who underwent TTT and an exercise treadmill test (ETT) were analyzed.
Forty-five had ST-segment changes/depressions during TTT (91% female, average age 36 years). Of the 45, three had ST-segment depression during ETT; all three had negative exercise stress echocardiograms (ESEs). Two others had ST-segment depressions on ETT (but not TTT), with negative ESEs.
In a cohort of young, female, otherwise healthy patients with POTS, ST-segment changes occurred in a significant portion (18%) of patients during TTT. When evaluated with exercise stress testing, these patients had no evidence of underlying ischemia on ETT or ESE.
先前的研究报告了倾斜台试验（TTT）期间的心电图（ECG）变化，特别是复极期间的 ST 段和 T 波变化。与缺血评估的相关性尚不清楚。本研究的目的是分析体位性心动过速综合征（POTS）年轻、健康患者群体在 TTT 期间 ST 段变化的发生率，并将其与运动应激试验结果相关联。
分析了 255 例接受 TTT 和运动平板试验（ETT）的 POTS 患者。
45 例在 TTT 期间出现 ST 段变化/压低（91%为女性，平均年龄 36 岁）。在这 45 例中，有 3 例在 ETT 期间出现 ST 段压低；这 3 例均有阴性运动应激超声心动图（ESE）。另外 2 例在 ETT 上（而非 TTT）出现 ST 段压低，ESE 阴性。
在一组年轻、女性、健康的 POTS 患者中，在 TTT 期间，ST 段变化在相当一部分（18%）患者中发生。当用运动应激测试评估时，这些患者在 ETT 或 ESE 上没有潜在缺血的证据。
