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青少年特发性脊柱侧凸术后 5 年随访时的背痛和生活质量:与健康对照组和未经治疗的特发性脊柱侧凸患者的比较。

Back Pain and Quality of Life After Surgical Treatment for Adolescent Idiopathic Scoliosis at 5-Year Follow-up: Comparison with Healthy Controls and Patients with Untreated Idiopathic Scoliosis.

机构信息

Departments of Anaesthesia and Intensive Care (L.H. and T.M.) and Paediatric Orthopaedic Surgery (L.H., M.L., H.O., O.P., and I.H.), University of Turku and Turku University Hospital, Turku, Finland.

Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.

出版信息

J Bone Joint Surg Am. 2019 Aug 21;101(16):1460-1466. doi: 10.2106/JBJS.18.01370.

Abstract

BACKGROUND

Posterior spinal fusion with pedicle screws is the gold-standard treatment for adolescent idiopathic scoliosis (AIS); however, it is unclear whether this procedure results in improved long-term back pain and health-related quality of life compared with patients not surgically treated for AIS. The aim of the present study was to evaluate back pain and quality of life in surgically managed patients with a minimum follow-up of 5 years compared with patients with untreated AIS and a healthy control group.

METHODS

Fifty-five consecutive adolescent patients who underwent posterior pedicle screw instrumentation for AIS by a single orthopaedic surgeon were prospectively enrolled. At a minimum of 5 years postoperatively, 49 patients completed Scoliosis Research Society (SRS)-24 questionnaires, and data on reoperation were collected. Pain and quality-of-life parameters were compared with those of 49 age and sex-matched patients with untreated AIS and 49 healthy controls.

RESULTS

The major curve averaged 53° preoperatively and 12° at 2 years postoperatively. One reoperation (pedicle screw removal) was needed because of a new neurological deficit (transient). The SRS-24 pain, function, and total scores improved significantly from preoperatively to 5 years postoperatively (all p ≤ 0.016), with pain scores improving from 4.0 to 4.3 (p = 0.003). There was no association between pain scores and the preoperative major curve, instrumentation below L1, or postoperative rib hump. The surgical treatment group had significantly better pain, activity, and self-image domain scores at 5 years postoperatively compared with the untreated AIS group (all p ≤ 0.014), and similar pain, self-image, and activity domain scores compared with the healthy control group; however, function scores were significantly lower among patients in the surgical treatment group (p < 0.001).

CONCLUSIONS

Patients who underwent posterior spinal fusion with pedicle screws experienced improved back pain and health-related quality of life compared with patients with untreated AIS. Patients in the surgical treatment group had similar health-related quality of life to that of the healthy control group, except for function, which was significantly lower.

LEVEL OF EVIDENCE

Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.

摘要

背景

后路脊柱融合加椎弓根螺钉固定是青少年特发性脊柱侧凸(AIS)的金标准治疗方法;然而,与未经手术治疗的 AIS 患者相比,后路脊柱融合加椎弓根螺钉固定是否能改善长期背痛和健康相关生活质量尚不清楚。本研究的目的是评估至少随访 5 年的手术治疗患者的背痛和生活质量,并与未经治疗的 AIS 患者和健康对照组进行比较。

方法

前瞻性纳入 55 例由同一位骨科医生行后路椎弓根螺钉内固定治疗的青少年 AIS 连续患者。术后至少 5 年,49 例患者完成了脊柱侧凸研究协会(SRS)-24 问卷,收集了再手术的数据。将疼痛和生活质量参数与 49 例年龄和性别匹配的未经治疗的 AIS 患者和 49 例健康对照组进行比较。

结果

术前主弯平均 53°,术后 2 年 12°。由于新的神经功能障碍(一过性),需要进行一次翻修手术(椎弓根螺钉取出)。SRS-24 疼痛、功能和总分从术前到术后 5 年显著改善(均 p≤0.016),疼痛评分从 4.0 分改善到 4.3 分(p=0.003)。疼痛评分与术前主弯、L1 以下固定或术后肋骨隆凸无相关性。术后 5 年,手术治疗组的疼痛、活动和自我形象域评分明显优于未经治疗的 AIS 组(均 p≤0.014),与健康对照组的疼痛、自我形象和活动域评分相似;然而,手术治疗组的功能评分明显较低(p<0.001)。

结论

后路脊柱融合加椎弓根螺钉固定的患者与未经治疗的 AIS 患者相比,背痛和健康相关生活质量得到改善。手术治疗组的患者与健康对照组的健康相关生活质量相似,除了功能,功能明显较低。

证据水平

治疗水平 III。有关证据水平的完整描述,请参阅作者指南。

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