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经F氟脱氧葡萄糖正电子发射断层扫描检测发现的无存活心肌,在冠状动脉介入治疗后的功能及代谢改善情况。

Functional and metabolic improvement after coronary intervention for non-viable myocardium detected by F fluorodeoxyglucose positron emission tomography.

作者信息

Fukushima Kenji, Arashi Hiroyuki, Minami Yuichiro, Nakao Risako, Nagao Michinobu, Abe Koichiro

机构信息

Department of Diagnostic Imaging and Nuclear Medicine, Tokyo Women's Medical University, Tokyo, Japan.

Department of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.

出版信息

J Cardiol Cases. 2019 May 3;20(2):57-60. doi: 10.1016/j.jccase.2019.03.006. eCollection 2019 Aug.

Abstract

We report a case of a 64-year-old man suspected of myocardial infarction two months previously. Coronary angiography revealed total occlusion of the left anterior descending (LAD), and left ventriculography (LVG) showed remarkably reduced cardiac function and anterior dyskinesis. Electrocardiogram-gated thallium-201 Single Photon Emission Tomography (TL-SPECT) and F fluorodeoxyglucose positron emission tomography (FDG) were performed separately, and revealed large anterior myocardial infarction with markedly reduced tracer uptake, suggestive of non-viable myocardium. Percutaneous coronary intervention (PCI) was performed and stent was implanted successfully. Six months after PCI, LVG showed remarkable recovery in global function. Significant wall motion improvement and recovered glucose metabolism were observed in the infarcted myocardium despite having previously been diagnosed as lacking viability. < In patients with left ventricular dysfunction, revascularized myocardium can contribute to improve cardiac function and prognosis. This evidence was established for old, or chronic status of myocardial infarction which is defined as over one month from onset of acute myocardial infarction. In this case report, we suggest that it can be premature to determine myocardial viability using FDG for the patient with under pre-chronic status after myocardial infarction due to underestimation on myocardial FDG uptake.>.

摘要

我们报告一例64岁男性患者,两个月前被怀疑患有心肌梗死。冠状动脉造影显示左前降支(LAD)完全闭塞,左心室造影(LVG)显示心脏功能显著降低且前壁运动障碍。分别进行了心电图门控铊-201单光子发射断层扫描(TL-SPECT)和氟脱氧葡萄糖正电子发射断层扫描(FDG),结果显示大面积前壁心肌梗死,示踪剂摄取显著降低,提示心肌无活性。进行了经皮冠状动脉介入治疗(PCI)并成功植入支架。PCI术后6个月,LVG显示整体功能显著恢复。尽管之前被诊断为心肌无活性,但在梗死心肌中观察到明显的壁运动改善和葡萄糖代谢恢复。<在左心室功能不全的患者中,再灌注的心肌可有助于改善心脏功能和预后。这一证据适用于陈旧性或慢性心肌梗死状态,即急性心肌梗死发病超过一个月。在本病例报告中,我们认为对于心肌梗死后处于亚慢性状态的患者,由于心肌FDG摄取被低估,使用FDG来确定心肌活性可能为时过早。>

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