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应激性心肌病后并发左心室流出道梗阻:一场危险的接力赛。

Reverse takotsubo cardiomyopathy followed by left ventricle outflow tract obstruction: A dangerous relay race.

作者信息

Mele Marco, Pepe Martino, Maggi Alessandro, Troccoli Rossella, Rutigliano David, Villella Alessandro

机构信息

Cardiology Department, Masselli Mascia Hospital, San Severo (FG), ASL FG, Italy.

Institute of Cardiology, University of Bari, Bari, Italy.

出版信息

J Cardiol Cases. 2019 Apr 20;20(2):61-64. doi: 10.1016/j.jccase.2019.04.001. eCollection 2019 Aug.

DOI:10.1016/j.jccase.2019.04.001
PMID:31440314
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6698232/
Abstract

Reverse takotsubo cardiomyopathy (rTTC) is a less frequent variant of takotsubo cardiomyopathy (TTC) with several differences about epidemiology and clinical aspects. While left ventricular outflow tract (LVOT) obstruction is relatively frequent in TTC patients, this complication has not been reported in the setting of rTTC yet. We describe the case of a female patient with rTTC complicated by LVOT obstruction and systolic anterior motion of mitral valve: the onset of these findings coincided with the regression of wall motion abnormalities. This dangerous "relay race" seems to be not casual but related to the characteristics of rTTC and should be always expected and prevented. < Left ventricle outflow tract obstruction with systolic anterior motion of mitral valve is an insidious complication that may be associated with reverse takotsubo cardiomyopathy and not only with the classic takotsubo cardiomyopathy. This complication appears to be delayed and should be always expected. Close echocardiographic monitoring, careful fluid support and early start of beta-blocker therapy may prevent it.>.

摘要

反向性应激性心肌病(rTTC)是应激性心肌病(TTC)中较罕见的一种类型,在流行病学和临床方面存在一些差异。虽然左心室流出道(LVOT)梗阻在TTC患者中相对常见,但在rTTC患者中尚未有该并发症的报道。我们描述了一例患有rTTC并伴有LVOT梗阻和二尖瓣收缩期前向运动的女性患者:这些表现的出现与室壁运动异常的消退同时发生。这种危险的“接力赛”似乎并非偶然,而是与rTTC的特征有关,应始终予以警惕并预防。<二尖瓣收缩期前向运动伴左心室流出道梗阻是一种隐匿性并发症,可能与反向性应激性心肌病有关,而不仅与经典的应激性心肌病有关。这种并发症似乎出现较晚,应始终予以警惕。严密的超声心动图监测、谨慎的液体支持以及早期开始使用β受体阻滞剂治疗可能预防该并发症。>

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本文引用的文献

1
A case of reverse takotsubo cardiomyopathy caused by an eating disorder.一例由饮食失调引起的反向应激性心肌病病例。
J Cardiol Cases. 2016 Nov 24;15(3):77-79. doi: 10.1016/j.jccase.2016.10.015. eCollection 2017 Mar.
2
International Expert Consensus Document on Takotsubo Syndrome (Part I): Clinical Characteristics, Diagnostic Criteria, and Pathophysiology.国际 Takotsubo 综合征专家共识文件(第一部分):临床特征、诊断标准和病理生理学。
Eur Heart J. 2018 Jun 7;39(22):2032-2046. doi: 10.1093/eurheartj/ehy076.
3
Late-onset dynamic outflow tract gradient in the setting of tako-tsubo cardiomyopathy: An interesting phenomenon with potential implications?应激性心肌病背景下的迟发性动态流出道梯度:一种具有潜在影响的有趣现象?
Indian Heart J. 2017 May-Jun;69(3):328-330. doi: 10.1016/j.ihj.2016.12.004. Epub 2017 Jan 2.
4
Differences between Takotsubo cardiomyopathy and reverse Takotsubo cardiomyopathy associated with subarachnoid hemorrhage.与蛛网膜下腔出血相关的应激性心肌病和反向应激性心肌病之间的差异。
Int J Cardiol Heart Vasc. 2016 May 11;11:99-103. doi: 10.1016/j.ijcha.2016.05.010. eCollection 2016 Jun.
5
Transient left ventricular outflow tract obstruction with systolic anterior motion of the mitral valve: A stunning cause.伴有二尖瓣收缩期前向运动的短暂性左心室流出道梗阻:一个惊人的病因。
Echocardiography. 2017 Jul;34(7):1089-1091. doi: 10.1111/echo.13553. Epub 2017 May 12.
6
Prevalence, associated factors and management implications of left ventricular outflow tract obstruction in takotsubo cardiomyopathy: a two-year, two-center experience.应激性心肌病左心室流出道梗阻的患病率、相关因素及管理意义:一项为期两年的双中心研究经验
BMC Cardiovasc Disord. 2014 Oct 22;14:147. doi: 10.1186/1471-2261-14-147.
7
Reverse takotsubo cardiomyopathy: two case reports and review of the literature.反向性应激性心肌病:两例病例报告及文献综述
J Med Case Rep. 2013 Mar 19;7:84. doi: 10.1186/1752-1947-7-84.
8
The clinical characteristics, laboratory parameters, electrocardiographic, and echocardiographic findings of reverse or inverted takotsubo cardiomyopathy: comparison with mid or apical variant.逆或倒置性心肌气球样变心肌病的临床特征、实验室参数、心电图和超声心动图表现:与中间或心尖部变异型的比较。
Clin Cardiol. 2011 Nov;34(11):693-9. doi: 10.1002/clc.20953. Epub 2011 Oct 26.
9
Reverse or inverted takotsubo cardiomyopathy (reverse left ventricular apical ballooning syndrome) presents at a younger age compared with the mid or apical variant and is always associated with triggering stress.反向型或倒置型应激性心肌病(左心室心尖部反向膨出综合征)与中部或心尖部变异型相比,发病年龄较轻,且总是与诱发应激相关。
Congest Heart Fail. 2010 Nov-Dec;16(6):284-6. doi: 10.1111/j.1751-7133.2010.00188.x. Epub 2010 Oct 29.
10
Dynamic left ventricular outflow tract obstruction without basal septal hypertrophy, caused by catecholamine therapy and volume depletion.由儿茶酚胺治疗和血容量减少引起的无基底间隔肥厚的动态左心室流出道梗阻。
Korean J Intern Med. 2008 Jun;23(2):106-9. doi: 10.3904/kjim.2008.23.2.106.