South Australian Institute of Ophthalmology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Clin Exp Ophthalmol. 2019 Dec;47(9):1131-1137. doi: 10.1111/ceo.13618. Epub 2019 Sep 4.
This study introduces a new technique in the assessment of nasolacrimal drainage with magnetic resonance imaging.
To describe a new dynamic magnetic resonance dacryocystography (MRDCG) protocol and report normative findings on asymptomatic lacrimal drainage systems.
A prospective observational study at the Royal Adelaide Hospital.
Seventeen patients with unilateral epiphora were prospectively recruited.
Patients underwent dynamic MRDCG. The time-resolved angiography with interleaved stochastic trajectories (TWIST) sequence was used to visualise contrast flow through the lacrimal drainage system.
Tear transit times and anatomical dimensions were measured.
Dynamic MRDCG with TWIST sequence reliably demonstrated contrast flow. Tear transit times and anatomical dimensions were comparable to previously reported values in other imaging modalities.
Dynamic MRDCG provides good structural and temporal resolution to the assessment of lacrimal outflow obstructions. The physiological nature of this modality allows potential assessment for functional obstruction and future research on tear flow assessment.
本研究在磁共振成像评估鼻泪管方面引入了一种新技术。
描述一种新的动态磁共振泪道造影（MRDCG）方案，并报告无症状泪液引流系统的正常发现。
皇家阿德莱德医院的前瞻性观察研究。
17 名单侧溢泪的患者被前瞻性招募。
患者接受动态 MRDCG 检查。使用时间分辨血管造影与交错随机轨迹（TWIST）序列来可视化泪液引流系统中的对比剂流动。
泪液通过时间和解剖学尺寸的测量。
TWIST 序列的动态 MRDCG 可靠地显示了对比剂的流动。泪液通过时间和解剖学尺寸与其他影像学模式的先前报道值相当。
动态 MRDCG 为评估泪液流出阻塞提供了良好的结构和时间分辨率。该方法的生理学特性允许对功能性阻塞进行潜在评估，并为未来的泪液流动评估研究提供了可能。
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