Division of Psychodermatology, Central Michigan University, Saginaw, Michigan.
Dermatol Ther. 2019 Sep;32(5):e13073. doi: 10.1111/dth.13073. Epub 2019 Sep 4.
Treatment of psychodermatological conditions, particularly body-focused repetitive behavior disorders, is often unsatisfactory. Various psychopharmacological and non-pharmacological treatments have been used to ameliorate the symptoms of these disorders. N-Acetylcysteine (NAC) is a newer modality in the treatment of these disorders. This short review focuses on pharmacology, mode of action, and use of NAC in common body-focused repetitive disorders such as trichotillomania, skin-picking disorders, and onychotillomania (nail biting). Current research and literature review have been evaluated and will be discussed.
治疗心理皮肤病况，特别是以身体为中心的重复性行为障碍，往往不尽如人意。已经使用了各种精神药理学和非药理学的治疗方法来改善这些障碍的症状。N-乙酰半胱氨酸（NAC）是这些障碍治疗的一种新方法。这篇简短的综述主要关注 NAC 的药理学、作用机制以及在常见的以身体为中心的重复性障碍中的应用，如拔毛癖、皮肤搔抓障碍和咬甲癖。评估了当前的研究和文献综述，并将进行讨论。
