Institut de Cancérologie de Lorraine, Department of Surgical Oncology, 6 avenue de Bourgogne, 54519 Vandoeuvre-lès-Nancy, France.
Institut de Cancérologie de Lorraine, Department of Surgical Oncology, 6 avenue de Bourgogne, 54519 Vandoeuvre-lès-Nancy, France.
Am J Otolaryngol. 2019 Nov-Dec;40(6):102271. doi: 10.1016/j.amjoto.2019.08.002. Epub 2019 Aug 3.
We evaluated a cohort of advanced hypopharyngeal squamous cell carcinoma, treated with conservative surgery, reconstruction with infrahyoid flap and radio-chemotherapy.
We used partial pharyngo-laryngectomy and radio-chemotherapy to treat fifty-seven patients with stage III-IV hypopharyngeal SCC from November 1994 to December 2011. Clinical examination and speech therapy evaluation were used for estimation of laryngeal function.
All patients received a partial pharyngo-laryngectomy. All patients underwent neck dissection; 56 patients received bilateral neck dissection. Reconstruction was achieved by infra-hyoid flap. Five-year overall and disease-specific survival rates were 54.4% and 61.4%, respectively. Successful laryngeal function preservation with complete five-year remission was achieved in 44% of the patients.
Selected even if advanced carcinomas of the hypopharynx maybe treated with partial pharyngo-laryngectomy with reconstruction with pedicled flap. Both oncological and functional results showed a good outcome.
我们评估了一组接受保守性手术、采用下咽肌皮瓣重建和放化疗治疗的晚期下咽鳞癌患者。
我们采用部分喉咽切除术和放化疗治疗 1994 年 11 月至 2011 年 12 月的 57 例 III-IV 期下咽鳞癌患者。临床检查和言语治疗评估用于估计喉功能。
所有患者均接受了部分喉咽切除术。所有患者均行颈清扫术；56 例患者行双侧颈清扫术。采用下咽部肌皮瓣进行重建。5 年总生存率和疾病特异性生存率分别为 54.4%和 61.4%。44%的患者成功保留了完整的喉功能，且完全缓解持续 5 年。
即使是晚期下咽癌，也可选择采用带蒂皮瓣重建的部分喉咽切除术进行治疗。肿瘤学和功能结果均显示出良好的效果。
