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Controlled release of diphosphonates from synthetic polymers to inhibit calcification.

作者信息

Golomb G

机构信息

Department of Pharmacy, School of Pharmacy, Hebrew University of Jerusalem, Israel.

出版信息

J Biomater Appl. 1987 Oct;2(2):266-89. doi: 10.1177/088532828700200205.

Abstract

Calcification is the most frequent cause of the failure of bioprosthetic heart valves fabricated from glutaraldehyde pretreated porcine aortic valves or bovine pericardium. Formulation and evaluation of controlled-release drug delivery system to inhibit bioprosthetic heart valve calcification is reviewed.

摘要

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