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[脑转移瘤的再照射:过去五年回顾]

[Reirradiation of brain metastasis: Review of the last five years].

作者信息

Nguyen M-N, Noel G, Antoni D

机构信息

Département de radiothérapie, Centre de lutte contre le cancer Paul-Strauss, 3, rue de la Porte de l'hôpital, BP 42, 67065 Strasbourg cedex, France.

Département de radiothérapie, Centre de lutte contre le cancer Paul-Strauss, 3, rue de la Porte de l'hôpital, BP 42, 67065 Strasbourg cedex, France; Université de Strasbourg, CNRS, IPHC UMR 7178, Centre Paul Strauss, unicancer, 67000 Strasbourg, France.

出版信息

Cancer Radiother. 2019 Oct;23(6-7):531-540. doi: 10.1016/j.canrad.2019.07.144. Epub 2019 Aug 22.

Abstract

No recommandations have been established for reirradiation of brain metastases yet. The purpose of this review is to analyse the data of the five last years about the feasibility, efficacy and tolerance of reirradiation of brain metastases. Reirradiation can be 3D conformal or stereotactic. Whole brain irradiation seems appropriate for multiple brain metastases in order to obtain symptomatic relief, with or without supportive care. Stereotactic reirradiation has shown satisfying results in terms of overall survival, local control, without significant toxicity. Prospective trials are necessary in order to validate consensual recommandations.

摘要

目前尚未制定关于脑转移瘤再程放疗的推荐方案。本综述的目的是分析过去五年中有关脑转移瘤再程放疗的可行性、疗效和耐受性的数据。再程放疗可以是三维适形放疗或立体定向放疗。全脑照射似乎适用于多发性脑转移瘤,无论有无支持治疗,以缓解症状。立体定向再程放疗在总生存期、局部控制方面显示出令人满意的结果,且无明显毒性。有必要进行前瞻性试验以验证共识性推荐方案。

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