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[动态心电图对刚果布拉柴维尔缺血性中风病因诊断的贡献]

[Contribution of Holter ECG in the etiologic diagnosis of the ischemic stroke in Brazzaville, Congo].

作者信息

Ikama Stéphane Méo, Makani Jospin, Mpandzou Ghislain, Ossou-Nguiet Paul Macaire, Nsitou Bernice Mesmer, Lambi Munka Nkalla, Matali Edgard, Gombet Thierry Raoul, Kaky Suzy Gisèle Kimbally

机构信息

Service de Cardiologie, Centre Hospitalier Universitaire de Brazzaville, Congo.

Service de Neurologie, Centre Hospitalier Universitaire de Brazzaville, Congo.

出版信息

Pan Afr Med J. 2018 Dec 19;31:235. doi: 10.11604/pamj.2018.31.235.17709. eCollection 2018.

Abstract

To determine the prevalence of the rhythmic disorders during ischemic stroke, and to identify the predictive factors of paroxysmal atrial fibrillation (PAF). It was about a cross-sectional study, descriptive and analytical, conducted to Brazzaville between january 2012 and december 2016. It related to a consecutive series of 267 patients victims of a transient ischemic attack (n = 17) or ischemic stroke (n = 250), documented by cerebral tomodensitometry or brain MRI. All these patients profited from a recording 24h Holter ECG, carried out within the framework of etiologic research. The principal recorded rhythmic anomalies were indexed and the logistic regression allowed the identification of the predictive factors of PAF. They were 164 men (61.4%) and 103 women (38.6%), old on average of 60.2 ± 12.1 years. The identified cardiovascular risk factors were hypertension (80.1%), diabetes (13.5%), and tobacco use (6.7%). The 24h Holter ECG, normal in 216 cases (81%), was pathological in 51 cases (19%). The principal recorded anomalies consisted into ventricular ectopic beats (n = 32), PAF (n = 7), supraventricular ectopic beats (n = 5), non-sustained ventricular tachycardia (n = 4), sustained ventricular tachycardia (n = 2), and type 2 atrio-ventricular block (n = 1). The frequency of PAF was 2.6%. In bivariate analysis, it was not noted correlation between PAF and sex (p = 0.55), hypertension (p = 0.42), diabetes (p = 0.64), and tobacco use (p = 0.61). In multivariate analysis, only the age was the predictive factor of PAF during ischemic stroke (p = 0.0134). It comes out from this preliminary study that the emboligenous arrhythmias are relatively rare during ischemic stroke in Brazzaville. PAF, though little attends, remains primarily correlated at the age. Its systematic research at the old subjects contributes to improve the assumption of responsibility.

摘要

确定缺血性中风期间节律紊乱的患病率,并确定阵发性心房颤动(PAF)的预测因素。这是一项于2012年1月至2016年12月在布拉柴维尔进行的横断面研究,兼具描述性和分析性。该研究涉及连续的267例短暂性脑缺血发作(n = 17)或缺血性中风(n = 250)患者,均通过脑密度测定或脑部MRI记录在案。所有这些患者均在病因研究框架内接受了24小时动态心电图记录。对记录的主要节律异常进行索引,并通过逻辑回归确定PAF的预测因素。其中男性164例(61.4%),女性103例(38.6%),平均年龄60.2±12.1岁。确定的心血管危险因素为高血压(80.1%)、糖尿病(13.5%)和吸烟(6.7%)。24小时动态心电图检查,216例(81%)结果正常,51例(19%)异常。记录的主要异常包括室性早搏(n = 32)、PAF(n = 7)、室上性早搏(n = 5)、非持续性室性心动过速(n = 4)、持续性室性心动过速(n = 2)和二度房室传导阻滞(n = 1)。PAF的发生率为2.6%。在双变量分析中,未发现PAF与性别(p = 0.55)、高血压(p = 0.42)、糖尿病(p = 0.64)和吸烟(p = 0.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/076a/6691285/d2885dfd17c2/PAMJ-31-235-g001.jpg

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