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婴儿肥厚型心肌病和支气管肺炎致 11 月龄婴儿意外死亡

Infantile Hypertrophic Cardiomyopathy and Bronchopneumonia as Causes of an Unexpected Death in an 11-Month-Old Child.

机构信息

Dipartimento di Scienze della Sanità Pubblica e Pediatriche - Sezione di Medicina Legale - "Università degli Studi di Torino", University of Turin, Torino, Italy.

出版信息

Fetal Pediatr Pathol. 2020 Oct;39(5):452-454. doi: 10.1080/15513815.2019.1655820. Epub 2019 Aug 26.

Abstract

Hypertrophic cardiomyopathy is characterized by intrinsic myocardial hypertrophy that is not consequent to hemodynamic stimuli. Infantile hypertrophic cardiomyopathy (<1 year of age) has a frequency of about 3.6 per 1 million children, is usually diagnosed in utero, at birth, or in the first months of life. The most common outcome of this form is heart failure that may result in the death of the child. We present an 11-month old infant with hypertrophic cardiomyopathy, complicated by terminal bronchopneumonia, without the typical clinical signs/symptoms in which the diagnosis was made only after postmortem examination. The present report depicts that IHCM may present with the unexpected death of an infant.

摘要

肥厚型心肌病的特征是心肌固有肥厚,与血流动力学刺激无关。婴儿肥厚型心肌病(<1 岁)的发病率约为每 100 万儿童 3.6 例,通常在宫内、出生时或生命的头几个月被诊断出来。这种形式最常见的结果是心力衰竭,可能导致儿童死亡。我们介绍了一例 11 个月大的婴儿,患有肥厚型心肌病,并发终末期支气管肺炎,没有典型的临床症状/体征,仅在尸检后才做出诊断。本报告表明,IHCM 可能表现为婴儿的意外死亡。

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