通过哈里斯-本尼迪克特方程评估的急性胰腺炎患者能量消耗与间接测热法的比较。

Energy expenditure in acute pancreatitis evaluated by the Harris-Benedict equation compared with indirect calorimetry.

作者信息

Valainathan S, Boukris A, Arapis K, Schoch N, Goujon G, Konstantinou D, Bécheur H, Pelletier A L

机构信息

Service d'Hépatogastroentérologie, Hôpital Bichat-Claude Bernard, 75018, Paris, France.

Service de Chirurgie Digestive, Hôpital Bichat-Claude Bernard, 75018, Paris, France.

出版信息

Clin Nutr ESPEN. 2019 Oct;33:57-59. doi: 10.1016/j.clnesp.2019.07.007. Epub 2019 Jul 27.

DOI:10.1016/j.clnesp.2019.07.007

PMID:31451277

Abstract

OBJECTIVES

Enteral nutrition (EN) is recommended for severe acute pancreatitis (AP) and for biliary AP if cholecystectomy is delayed. Energy expenditure (EE) is calculated using the Harris-Benedict equation (HBE), but indirect calorimetry (IC) can also be employed. We wished to compare EE evaluated by the HBE equation, modified HBE (mHBE) and IC at study inclusion and 1 month after AP resolution.

METHODS

We undertook a single-center prospective study in Paris, France.

RESULTS

Among 35 patients, 19 had biliary AP and 11 alcoholic-related AP. Eleven cases had severe AP. There was no significant difference between EE calculated by the HBE and that using IC at study inclusion. However, the EE calculated by the mHBE was significantly higher than that calculated using IC. For severe AP, the HBE underestimated EE whereas the mHBE overestimated it. No difference was found based on the cause of AP. There was no difference between methods for EE at 30 days.

CONCLUSIONS

The HBE underestimated EE for severe AP, whereas the mHBE overestimated it. IC seems to be the best means of EE evaluation for AP.

摘要

目的

对于重症急性胰腺炎（AP）以及胆囊切除术延迟的胆源性AP，推荐采用肠内营养（EN）。能量消耗（EE）可通过哈里斯-本尼迪克特方程（HBE）计算，但也可采用间接测热法（IC）。我们希望比较在研究纳入时以及AP缓解后1个月，通过HBE方程、改良HBE（mHBE）和IC评估的EE。

方法

我们在法国巴黎进行了一项单中心前瞻性研究。

结果

35例患者中，19例为胆源性AP，11例为酒精性相关AP。11例为重症AP。在研究纳入时，通过HBE计算的EE与使用IC计算的EE之间无显著差异。然而，通过mHBE计算的EE显著高于使用IC计算的EE。对于重症AP，HBE低估了EE，而mHBE高估了EE。基于AP的病因未发现差异。30天时EE评估方法之间无差异。