Rutovic Stela, Kadojic Dragutin, Dikanovic Marinko, Solic Kresimir, Malojcic Branko
Polyclinic Glavic Zagreb, Osijek School of Medicine, Josip Juraj Strossmayer University of Osijek, Zagreb, Croatia.
Department of Neurology, University Hospital Centre Osijek, Osijek School of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.
Acta Neurol Belg. 2021 Apr;121(2):437-442. doi: 10.1007/s13760-019-01200-9. Epub 2019 Aug 26.
Although most often considered a consequence of traumatic event, post-traumatic stress disorder (PTSD) also occurs after illness. The aim of this study was to establish prevalence of PTSD in patients with ischaemic stroke (IS) and its correlation to lesion location, degree of disability, age, gender and marital status. The study included 85 patients with IS. PTSD was diagnosed using a modified version of the PTSD Checklist Specific for a stressor (PCL-S). Depression and anxiety were assessed using Hospital Anxiety and Depression Scale (HADS). We defined stroke localisation as right cerebral hemisphere, left cerebral hemisphere, brainstem and cerebellum. Stroke severity was measured using the modified Rankin scale (mRS). Demographic information including age, gender and marital status was collected from medical history. Of the 85 patients with IS, 11 (12.9%) fulfilled PCL-S criteria for PTSD. We found a positive correlation between PTSD and higher degree of disability, P < 0.001. Patients with PTSD had lesions more frequently localised in the right cerebral hemisphere and the brainstem. We found no statistically significant correlation of PTSD with age, gender and marital status. Our results show that a significant number of IS patients develop PTSD after IS. Determining correlates of post-stroke PTSD can help to identify those at higher risk for its development. If proven by additional large sample studies, more patients can benefit from screening for the PTSD symptoms.
尽管创伤后应激障碍（PTSD）通常被认为是创伤性事件的后果，但在患病后也会出现。本研究的目的是确定缺血性中风（IS）患者中PTSD的患病率及其与病变位置、残疾程度、年龄、性别和婚姻状况的相关性。该研究纳入了85例IS患者。使用针对应激源的PTSD检查表（PCL-S）的修订版来诊断PTSD。使用医院焦虑抑郁量表（HADS）评估抑郁和焦虑情况。我们将中风定位定义为右大脑半球、左大脑半球、脑干和小脑。使用改良Rankin量表（mRS）测量中风严重程度。从病史中收集包括年龄、性别和婚姻状况在内的人口统计学信息。在85例IS患者中，11例（12.9%）符合PCL-S的PTSD标准。我们发现PTSD与更高的残疾程度之间存在正相关，P<0.001。PTSD患者的病变更常位于右大脑半球和脑干。我们发现PTSD与年龄、性别和婚姻状况之间无统计学显著相关性。我们的结果表明，相当数量的IS患者在中风后会发生PTSD。确定中风后PTSD的相关因素有助于识别那些发生PTSD风险较高的患者。如果通过更多的大样本研究得到证实，更多患者可从PTSD症状筛查中获益。
