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阴囊局限性巨大孤立性纤维瘤:1例罕见病例报告及文献复习

Localized giant solitary fibrous tumor of the scrotum: a rare case report and literature review.

作者信息

Jiang Shuangjian, Yang Yun, Mo Chengqiang, Chen Lingwu, Qiu Shaopeng, Huang Bin, Chen Junxing

机构信息

Department of Urology, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.

Department of Anesthesia Surgery Center, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.

出版信息

J Int Med Res. 2019 Nov;47(11):5802-5808. doi: 10.1177/0300060519869140. Epub 2019 Aug 27.

DOI:10.1177/0300060519869140
PMID:31452410
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6862882/
Abstract

BACKGROUND

A solitary fibrous tumor (SFT) is a fibroblastic mesenchymal tumor initially thought to originate from the pleura but that may arise at almost any anatomic site. It is mostly benign, and surgical resection is usually the best treatment option. An SFT involving the scrotum is extremely rare. Case presentation: We herein report an uncommon case of a 22-year-old man who presented with a huge asymptomatic scrotal mass that had begun growing 3 years before presentation. Contrast-enhanced computed tomography revealed a heterogeneous, well-circumscribed scrotal mass with soft tissue density. No invasion of the surrounding organs, distal metastasis, or lymph node swelling was present. Complete resection of the mass was successfully performed. The specimen was a 14.5 × 12.0 × 9.5 cm encapsulated tumor that weighed 970 g. After pathological analysis, we confirmed the diagnosis of SFT. This diagnosis was based on clinical findings, histological morphology, and immunohistochemistry. No recurrence or metastasis was observed during a 3-year follow-up.

CONCLUSION

SFTs have an unpredictable clinical course, and they are difficult to diagnose and easy to misdiagnose. A scrotal location is extremely rare. Complete resection of the mass is the treatment of choice and is associated with a high success rate and low recurrence rate.

摘要

背景

孤立性纤维瘤(SFT)是一种成纤维细胞性间叶组织肿瘤,最初被认为起源于胸膜,但几乎可发生于任何解剖部位。它大多为良性,手术切除通常是最佳治疗选择。累及阴囊的SFT极为罕见。病例报告:我们在此报告一例罕见病例,一名22岁男性,出现一个巨大的无症状阴囊肿块,该肿块在就诊前3年开始生长。增强计算机断层扫描显示一个边界清晰、密度不均的阴囊软组织肿块。未见周围器官侵犯、远处转移或淋巴结肿大。成功地对肿块进行了完整切除。标本为一个14.5×12.0×9.5cm的包膜完整肿瘤,重970g。经病理分析,确诊为SFT。该诊断基于临床表现、组织形态学和免疫组化。在3年随访期间未观察到复发或转移。

结论

SFT的临床病程不可预测,诊断困难且易误诊。阴囊部位极为罕见。完整切除肿块是首选治疗方法,成功率高且复发率低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ba/6862882/ca68681122a6/10.1177_0300060519869140-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ba/6862882/2192d3a8324c/10.1177_0300060519869140-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ba/6862882/bd158ab1aa51/10.1177_0300060519869140-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ba/6862882/33f0f67720b7/10.1177_0300060519869140-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ba/6862882/ca68681122a6/10.1177_0300060519869140-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ba/6862882/2192d3a8324c/10.1177_0300060519869140-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ba/6862882/bd158ab1aa51/10.1177_0300060519869140-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ba/6862882/33f0f67720b7/10.1177_0300060519869140-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ba/6862882/ca68681122a6/10.1177_0300060519869140-fig4.jpg

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Medicine (Baltimore). 2017 Dec;96(48):e8854. doi: 10.1097/MD.0000000000008854.
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