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Clinical application of chromosomal microarray analysis for the prenatal diagnosis of chromosomal abnormalities and copy number variations in fetuses with congenital heart disease.染色体微阵列分析在先天性心脏病胎儿染色体异常和拷贝数变异产前诊断中的临床应用。
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Comparing the accuracy of obstetric sonography and fetal echocardiography during pediatric cardiology consultation in the prenatal diagnosis of congenital heart disease.比较产科超声检查与胎儿超声心动图在儿科心脏病会诊时对先天性心脏病产前诊断的准确性。
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心脏外科医生在先天性心脏病在线产前咨询中的作用。

The role of cardiac surgeons in online prenatal counselling for congenital heart disease.

作者信息

Zhu Yaobin, Zhang Yaping, Ding Nan, Zhao Yudong, Ye Zankai, Fan Xing, Liu Yang, Shen Lei, Yi Hanlu, Li Zhiqiang

机构信息

Department of Cardiovascular Surgery II, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.

Department of Heart Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

出版信息

J Int Med Res. 2019 Oct;47(10):5270-5277. doi: 10.1177/0300060519869079. Epub 2019 Aug 27.

DOI:10.1177/0300060519869079
PMID:31452428
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6833391/
Abstract

OBJECTIVE

To explore the role of cardiac surgeons in prenatal online counselling for congenital heart disease.

METHODS

From January 2014 to December 2017, the author consulted on 400 cases of foetal cardiovascular abnormalities through the Good Doctor Online and WeChat online platforms. The author made appropriate pregnancy recommendations to patients and families using patient ultrasound reports and medical histories. Followed-up patients who chose to continue their pregnancy received postnatal advice.

RESULTS

There were 248 simple cardiac abnormalities and 152 complex cardiac abnormalities. Foetal chromosome examination detected 2 cases of trisomy 21 syndrome and 26 normal cases. Two mothers (0.8%) of simple cardiac abnormality foetuses and 103 (67.8%) mothers of complex cardiac abnormality foetuses chose induced abortion. A total of 246 mothers of simple cardiac abnormality foetuses chose to continue pregnancy and had good postnatal prognosis. Twenty-six mothers of complex cardiac abnormality foetuses chose to continue pregnancy; among these, there were 4 intrauterine deaths, 22 births, 4 deaths while awaiting surgery and 18 successful surgeries.

CONCLUSION

The Good Doctor Online and WeChat platforms facilitate communication with a wide audience. Cardiac surgeons can reduce the birth incidence and improve prenatal consultations for severe congenital heart disease through these platforms.

摘要

目的

探讨心脏外科医生在先天性心脏病产前在线咨询中的作用。

方法

2014年1月至2017年12月,作者通过好大夫在线和微信在线平台对400例胎儿心血管异常病例进行咨询。作者利用患者超声报告和病史为患者及其家属提供适当的妊娠建议。对选择继续妊娠的患者进行随访并给予产后建议。

结果

有248例单纯心脏异常和152例复杂心脏异常。胎儿染色体检查发现2例21三体综合征和26例正常病例。单纯心脏异常胎儿的2名母亲(0.8%)和复杂心脏异常胎儿的103名母亲(67.8%)选择了人工流产。共有246例单纯心脏异常胎儿的母亲选择继续妊娠,产后预后良好。26例复杂心脏异常胎儿的母亲选择继续妊娠;其中,有4例宫内死亡,22例出生,4例等待手术时死亡,18例手术成功。

结论

好大夫在线和微信平台便于与广大受众进行沟通。心脏外科医生可通过这些平台降低严重先天性心脏病的出生发病率并改善产前咨询。