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急性卒中后偏侧帕金森综合征和偏瘫:一例成功治疗的独特病例。

Acute Post-stroke Hemiparkinsonism and Hemiparesis: A Unique Case with Successful Therapy.

作者信息

Chandradevan Raguraj, Rutkofsky Ian H, Lynn Bryan, Kitchen Felisha L, Simmons Marcus L

机构信息

Internal Medicine, Coliseum Medical Centers, Macon, USA.

Psychiatry, Coliseum Medical Centers, Macon, USA.

出版信息

Cureus. 2019 Jun 20;11(6):e4950. doi: 10.7759/cureus.4950.

Abstract

The diagnosis of a new onset movement disorder after a stroke has important clinical implications. The early assessment and timely diagnosis of post-stroke disorders is essential for influencing long-term outcomes. Localizing lesions and determining the underlying etiology is vital in targeting appropriate therapy. New and sudden onset of hemiparkinsonism with hemiparesis, rigidity, and tremor following an acute ischemic stroke is described here. This presentation was clinically diagnosed as acute post-stroke parkinsonism (APSP). The patient's level of impairment was significant enough to compromise his activities of daily living (ADL), physical therapy (PT), and occupational therapy (OT) in an inpatient rehabilitation center. In the inpatient rehabilitation center, the patient received a trial of levodopa for suspected APSP. After levodopa therapy was initiated, we observed an improvement of his parkinsonian features with a sustained response and reached the conclusion that the clinical recognition of post-stroke parkinsonism treated with a targeted trial with levodopa may improve the quality of life. Proper treatment of APSP has the potential to provide the best opportunity for recovery and positively influence the long-term outcomes in similar patients.

摘要

中风后新发运动障碍的诊断具有重要的临床意义。中风后疾病的早期评估和及时诊断对于影响长期预后至关重要。定位病变并确定潜在病因对于选择合适的治疗方法至关重要。本文描述了急性缺血性中风后出现的伴有偏瘫、僵硬和震颤的偏侧帕金森综合征的新发和突然发作情况。该表现临床诊断为急性中风后帕金森综合征(APSP)。患者的损伤程度严重到足以影响其在住院康复中心的日常生活活动(ADL)、物理治疗(PT)和职业治疗(OT)。在住院康复中心,患者因疑似APSP接受了左旋多巴试验。开始左旋多巴治疗后,我们观察到其帕金森特征有所改善且反应持续,得出结论:通过左旋多巴靶向试验治疗中风后帕金森综合征的临床认识可能会改善生活质量。正确治疗APSP有可能为恢复提供最佳机会,并对类似患者的长期预后产生积极影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef22/6701904/ad4c033c8adb/cureus-0011-00000004950-i01.jpg

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