Graffeo Christopher S, Perry Avital, Rangel-Castilla Leonardo
Department of Neurologic Surgery, Mayo Clinic, 200 1st Street SW, Rochester, MN, USA.
Department of Radiology, Mayo Clinic, 200 1st Street SW, Rochester, MN, USA.
Heliyon. 2019 Aug 12;5(8):e02041. doi: 10.1016/j.heliyon.2019.e02041. eCollection 2019 Aug.
Brain arteriovenous malformations (AVM) are a complex and challenging subset of neurosurgical disease, the optimal treatment of which is nuanced and dependent on numerous patient- and disease-specific factors. Clinical features that may predispose toward resection as front-line treatment include lower grade lesions, particularly those in non-eloquent locations, as well as active pregnancy. In all AVM resections, minimization of risk to exposed healthy brain adjacent to the lesion is a key surgical principle. In this illustrative case report, we discuss the management of a young woman who presented with a new diagnosis of AVM following an intracranial hemorrhage, at which time she was also identified as newly pregnant. Resection via the contralateral transfalcine approach with preoperative embolization was recommended, the intraoperative and postoperative courses proceeded uneventfully, and the patient was cured of her AVM and went on to successfully deliver twins. Recording and description of procedure are shown in Video Case Report.
脑动静脉畸形(AVM)是神经外科疾病中一个复杂且具有挑战性的类型,其最佳治疗方法微妙且取决于众多患者和疾病特异性因素。可能倾向于将切除作为一线治疗的临床特征包括较低级别的病变,特别是那些位于非功能区的病变,以及处于妊娠期。在所有AVM切除术中,将病变邻近暴露的健康脑组织的风险降至最低是一项关键的手术原则。在本病例报告中,我们讨论了一名年轻女性的治疗情况,该女性在颅内出血后被新诊断为AVM,当时她也被确定为新怀孕。建议采用术前栓塞的对侧经镰状窦入路进行切除,手术过程顺利,术后患者的AVM得到治愈,并成功产下双胞胎。手术记录和描述见视频病例报告。