• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

监狱中的加巴喷丁类药物:一项滥用与成瘾研究。

Gabapentinoids in penitentiaries: An abuse and addiction research.

作者信息

İlhanlı İlker, Güder Necip, Gül Murat

机构信息

Department of Physical Medicine and Rehabilitation, School of Medicine, Giresun University, Giresun, Turkey.

Department of Physical Medicine and Rehabilitation, Giresun Physical Therapy and Rehabilitation Hospital, Giresun, Turkey.

出版信息

Turk J Phys Med Rehabil. 2017 Nov 27;63(4):318-328. doi: 10.5606/tftrd.2017.651. eCollection 2017 Dec.

DOI:10.5606/tftrd.2017.651
PMID:31453474
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6648079/
Abstract

OBJECTIVES

This study aims to examine the abuse and addiction of gabapentinoids in penal institutions.

PATIENTS AND METHODS

Between September 2014 and November 2014, a total of 1,639 participants were administered an electronic questionnaire investigating the drug use and addiction. The questionnaire was requested to be asked and filled by the officers in charge for all voluntary convicts and prisoners in all penitentiaries throughout Turkey.

RESULTS

The rate of answering the questions varied between 20.5% and 100%. It was found that 2% of the participants used pregabalin and gabapentin simultaneously, while 25.2% of them used multiple drugs. The usage rate of pregabalin and gabapentin was higher in some penitentiaries, compared to the normal population. There was a significant positive correlation between the use of gabapentinoids and multiple drugs and alcohol and drug addiction, various withdrawal symptoms, the number of going to the infirmary, and the number of referral to the hospital (p<0.05).

CONCLUSION

Although gabapentinoids seem to be used in the treatment of addiction, and are proved effective treatment agents. With a definite diagnosis, appropriate follow-up, and timely completion of the treatment, it is necessary to strictly control their use due to the probability of abuse and addiction.

摘要

目的

本研究旨在调查惩教机构中加巴喷丁类药物的滥用及成瘾情况。

患者与方法

2014年9月至2014年11月期间,共1639名参与者接受了一项关于药物使用及成瘾情况的电子问卷调查。该问卷由土耳其各地所有监狱的负责官员向所有自愿服刑的罪犯和囚犯进行询问并填写。

结果

回答问题的比例在20.5%至100%之间。发现2%的参与者同时使用普瑞巴林和加巴喷丁,而25.2%的参与者使用多种药物。与普通人群相比,某些监狱中普瑞巴林和加巴喷丁的使用率更高。加巴喷丁类药物的使用与多种药物及酒精和药物成瘾、各种戒断症状、去医务室的次数以及转诊至医院的次数之间存在显著正相关(p<0.05)。

结论

尽管加巴喷丁类药物似乎用于成瘾治疗,且被证明是有效的治疗药物。但鉴于存在滥用和成瘾的可能性,在明确诊断、适当随访并及时完成治疗的情况下,有必要严格控制其使用。

相似文献

1
Gabapentinoids in penitentiaries: An abuse and addiction research.监狱中的加巴喷丁类药物:一项滥用与成瘾研究。
Turk J Phys Med Rehabil. 2017 Nov 27;63(4):318-328. doi: 10.5606/tftrd.2017.651. eCollection 2017 Dec.
2
[On the risk of dependence on gabapentinoids].[关于加巴喷丁类药物的依赖风险]
Fortschr Neurol Psychiatr. 2018 Feb;86(2):82-105. doi: 10.1055/s-0043-122392. Epub 2017 Nov 27.
3
Gabapentinoid misuse, abuse and non-prescribed obtainment in a United States general population sample.美国普通人群样本中加巴喷丁类药物的误用、滥用和非处方获取情况。
Int J Clin Pharm. 2021 Aug;43(4):1055-1064. doi: 10.1007/s11096-020-01217-8. Epub 2021 Jan 2.
4
Gabapentinoid Abuse in France: Evidence on Health Consequences and New Points of Vigilance.法国的加巴喷丁类药物滥用:健康后果及新的警惕要点证据
Front Psychiatry. 2021 Feb 3;12:639780. doi: 10.3389/fpsyt.2021.639780. eCollection 2021.
5
How addictive are gabapentin and pregabalin? A systematic review.加巴喷丁和普瑞巴林的成瘾性如何?系统评价。
Eur Neuropsychopharmacol. 2017 Dec;27(12):1185-1215. doi: 10.1016/j.euroneuro.2017.08.430. Epub 2017 Oct 5.
6
Pregabalin and gabapentin in non-opioid poisoning deaths.普瑞巴林和加巴喷丁在非阿片类药物中毒死亡中的作用。
Forensic Sci Int. 2021 Jul;324:110830. doi: 10.1016/j.forsciint.2021.110830. Epub 2021 May 13.
7
Abuse and Misuse of Pregabalin and Gabapentin: A Systematic Review Update.普瑞巴林和加巴喷丁的滥用与误用:系统评价更新
Drugs. 2021 Jan;81(1):125-156. doi: 10.1007/s40265-020-01432-7.
8
A Hidden Pandemic? Abuse of Gabapentinoids: A Brief Review of Recent Studies.一场隐匿的大流行?加巴喷丁类药物的滥用:近期研究综述
Curr Drug Res Rev. 2025;17(1):5-9. doi: 10.2174/0125899775268780231002064605.
9
On the addictive power of gabapentinoids: a mini-review.关于加巴喷丁类药物的成瘾性:一篇综述短文
Psychiatr Danub. 2018 Jun;30(2):142-149. doi: 10.24869/psyd.2018.142.
10
Gabapentinoid Pharmacology in the Context of Emerging Misuse Liability.加巴喷丁类药物在新出现的滥用责任方面的药理学
J Clin Pharmacol. 2021 Aug;61 Suppl 2:S89-S99. doi: 10.1002/jcph.1833.

引用本文的文献

1
The effects of gabapentin and pregabalin on fracture healing: A histological, radiological, and biomechanical analysis.加巴喷丁和普瑞巴林对骨折愈合的影响:组织学、放射学及生物力学分析
Jt Dis Relat Surg. 2025 Jan 2;36(1):200-209. doi: 10.52312/jdrs.2025.2042. Epub 2024 Dec 18.
2
Pregabalin withdrawal in patients without psychiatric disorders taking a regular dose of pregabalin: A case series and literature review.未患有精神障碍且服用常规剂量普瑞巴林的患者中普瑞巴林撤药:病例系列和文献复习。
Neuropsychopharmacol Rep. 2021 Sep;41(3):434-439. doi: 10.1002/npr2.12195. Epub 2021 Aug 12.

本文引用的文献

1
Pregabalin abuse, dependence, and withdrawal: a case report.普瑞巴林滥用、依赖及戒断:一例报告
Am J Psychiatry. 2010 Jul;167(7):869. doi: 10.1176/appi.ajp.2010.09091269.
2
A signal for an abuse liability for pregabalin--results from the Swedish spontaneous adverse drug reaction reporting system.普瑞巴林滥用倾向信号——来自瑞典自发药物不良反应报告系统的结果。
Eur J Clin Pharmacol. 2010 Sep;66(9):947-53. doi: 10.1007/s00228-010-0853-y. Epub 2010 Jun 19.
3
Possible new ways in the pharmacological treatment of bipolar disorder and comorbid alcoholism.双相障碍及共病酒精使用障碍的药理学治疗新方法。
Neuropsychiatr Dis Treat. 2010 Mar 24;6:37-46. doi: 10.2147/ndt.s6741.
4
Identification of molecular targets associated with ethanol toxicity and implications in drug development.鉴定与乙醇毒性相关的分子靶标及其在药物开发中的意义。
Curr Pharm Des. 2010;16(11):1313-55. doi: 10.2174/138161210791034030.
5
Pregabalin in the treatment of alcohol and benzodiazepines dependence.普瑞巴林治疗酒精和苯二氮䓬类药物依赖。
CNS Neurosci Ther. 2010 Spring;16(1):45-50. doi: 10.1111/j.1755-5949.2009.00120.x.
6
New medications for the treatment of cocaine dependence.治疗可卡因依赖的新药。
Ann Ist Super Sanita. 2009;45(2):109-15.
7
Treatment of alcohol dependence in patients with co-morbid major depressive disorder--predictors for the outcomes with memantine and escitalopram medication.共病重度抑郁症患者酒精依赖的治疗——美金刚和艾司西酞普兰药物治疗效果的预测因素
Subst Abuse Treat Prev Policy. 2008 Oct 3;3:20. doi: 10.1186/1747-597X-3-20.
8
Aripiprazole in the treatment of patients with alcohol dependence: a double-blind, comparison trial vs. naltrexone.阿立哌唑治疗酒精依赖患者:与纳曲酮的双盲对照试验
J Psychopharmacol. 2009 Mar;23(2):123-9. doi: 10.1177/0269881108089596. Epub 2008 May 30.
9
Fibromyalgia: harmonizing science with clinical practice considerations.纤维肌痛:将科学与临床实践考量相结合
Pain Pract. 2008 May-Jun;8(3):177-89. doi: 10.1111/j.1533-2500.2008.00190.x. Epub 2008 Mar 18.
10
Topiramate for treating alcohol dependence: a randomized controlled trial.托吡酯治疗酒精依赖:一项随机对照试验。
JAMA. 2007 Oct 10;298(14):1641-51. doi: 10.1001/jama.298.14.1641.