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监狱中的加巴喷丁类药物:一项滥用与成瘾研究。

Gabapentinoids in penitentiaries: An abuse and addiction research.

作者信息

İlhanlı İlker, Güder Necip, Gül Murat

机构信息

Department of Physical Medicine and Rehabilitation, School of Medicine, Giresun University, Giresun, Turkey.

Department of Physical Medicine and Rehabilitation, Giresun Physical Therapy and Rehabilitation Hospital, Giresun, Turkey.

出版信息

Turk J Phys Med Rehabil. 2017 Nov 27;63(4):318-328. doi: 10.5606/tftrd.2017.651. eCollection 2017 Dec.

Abstract

OBJECTIVES

This study aims to examine the abuse and addiction of gabapentinoids in penal institutions.

PATIENTS AND METHODS

Between September 2014 and November 2014, a total of 1,639 participants were administered an electronic questionnaire investigating the drug use and addiction. The questionnaire was requested to be asked and filled by the officers in charge for all voluntary convicts and prisoners in all penitentiaries throughout Turkey.

RESULTS

The rate of answering the questions varied between 20.5% and 100%. It was found that 2% of the participants used pregabalin and gabapentin simultaneously, while 25.2% of them used multiple drugs. The usage rate of pregabalin and gabapentin was higher in some penitentiaries, compared to the normal population. There was a significant positive correlation between the use of gabapentinoids and multiple drugs and alcohol and drug addiction, various withdrawal symptoms, the number of going to the infirmary, and the number of referral to the hospital (p<0.05).

CONCLUSION

Although gabapentinoids seem to be used in the treatment of addiction, and are proved effective treatment agents. With a definite diagnosis, appropriate follow-up, and timely completion of the treatment, it is necessary to strictly control their use due to the probability of abuse and addiction.

摘要

目的

本研究旨在调查惩教机构中加巴喷丁类药物的滥用及成瘾情况。

患者与方法

2014年9月至2014年11月期间,共1639名参与者接受了一项关于药物使用及成瘾情况的电子问卷调查。该问卷由土耳其各地所有监狱的负责官员向所有自愿服刑的罪犯和囚犯进行询问并填写。

结果

回答问题的比例在20.5%至100%之间。发现2%的参与者同时使用普瑞巴林和加巴喷丁,而25.2%的参与者使用多种药物。与普通人群相比,某些监狱中普瑞巴林和加巴喷丁的使用率更高。加巴喷丁类药物的使用与多种药物及酒精和药物成瘾、各种戒断症状、去医务室的次数以及转诊至医院的次数之间存在显著正相关(p<0.05)。

结论

尽管加巴喷丁类药物似乎用于成瘾治疗,且被证明是有效的治疗药物。但鉴于存在滥用和成瘾的可能性,在明确诊断、适当随访并及时完成治疗的情况下,有必要严格控制其使用。

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