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Neurobehavioral pharmacology of cocaine.

作者信息

Dworkin S I, Smith J E

机构信息

Department of Psychiatry, Louisiana State University, School of Medicine, Shreveport 71130-3932.

出版信息

NIDA Res Monogr. 1988;88:185-98.

PMID:3145449
Abstract
摘要

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Neurobehavioral pharmacology of cocaine.可卡因的神经行为药理学
NIDA Res Monogr. 1988;88:185-98.
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Dopamine D1 or D2 receptor antagonism within the basolateral amygdala differentially alters the acquisition of cocaine-cue associations necessary for cue-induced reinstatement of cocaine-seeking.基底外侧杏仁核内的多巴胺 D1 或 D2 受体拮抗作用会以不同方式改变线索诱导的可卡因觅求恢复所必需的可卡因线索关联的习得。
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Cocaine binding sites related to drug self-administration.
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Preference for distinct functional conformations of the dopamine transporter alters the relationship between subjective effects of cocaine and stimulation of mesolimbic dopamine.对多巴胺转运体不同功能构象的偏好改变了可卡因主观效应与中脑边缘多巴胺刺激之间的关系。
Biol Psychiatry. 2014 Nov 15;76(10):802-9. doi: 10.1016/j.biopsych.2014.03.031. Epub 2014 Apr 19.
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Relations between stimulation of mesolimbic dopamine and place conditioning in rats produced by cocaine or drugs that are tolerant to dopamine transporter conformational change.可卡因或对多巴胺转运体构象变化具有耐受性的药物在大鼠中引起的中脑边缘多巴胺刺激与位置条件反射之间的关系。
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New medications for the treatment of cocaine dependence.用于治疗可卡因成瘾的新型药物。
Psychiatry (Edgmont). 2005 Dec;2(12):44-8.
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Discovery of drugs to treat cocaine dependence: behavioral and neurochemical effects of atypical dopamine transport inhibitors.治疗可卡因成瘾药物的发现：非典型多巴胺转运体抑制剂的行为学和神经化学效应
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Patterns of functional activity associated with cocaine self-administration in the rat change over time.
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Phasic firing of single neurons in the rat nucleus accumbens correlated with the timing of intravenous cocaine self-administration.大鼠伏隔核中单个神经元的相位性放电与静脉注射可卡因自我给药的时间相关。
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