极早产儿拔管准备预测模型。
A predictive model for extubation readiness in extremely preterm infants.
机构信息
Department of Pediatrics, Wayne State University, Detroit, MI, USA.
Department of Pediatrics, Duke University, Durham, NC, USA.
出版信息
J Perinatol. 2019 Dec;39(12):1663-1669. doi: 10.1038/s41372-019-0475-x. Epub 2019 Aug 27.
OBJECTIVE
To develop an estimator for predicting successful extubation for an individual preterm infant.
STUDY DESIGN
This was a retrospective study that included infants with birth weights ≤1250 g, who were admitted to a tertiary NICU over a 7-year period, received mechanical ventilation and had an elective extubation attempt within 60 days of age. Perinatal and periextubation characteristics were compared in the successful and failed extubation groups.
RESULTS
Of 621 screened infants, 312 were included. Extubation succeeded in 73% and failed in 27%. Adjusted factors associated with successful extubation included greater gestational age, chronologic age, pre-extubation pH and lower pre-extubation FiO, along with lower "peak" respiratory severity score in the first 6 h of age.
CONCLUSIONS
We used readily available demographic and clinical data to create an extubation readiness estimator that provides the probability of extubation success for an individual preterm infant (http://elasticbeanstalk-us-east-2-676799334712.s3-website.us-east-2.amazonaws.com/).
目的
开发一种预测个体早产儿拔管成功的估算器。
研究设计
这是一项回顾性研究，纳入了出生体重≤1250g、在 7 年内入住三级新生儿重症监护病房、接受机械通气并在出生后 60 天内进行选择性拔管尝试的婴儿。比较了成功和失败拔管组的围产期和拔管期特征。
结果
在筛选出的 621 名婴儿中，有 312 名被纳入研究。73%的婴儿拔管成功，27%的婴儿拔管失败。与成功拔管相关的调整因素包括更大的胎龄、时间年龄、预拔管时 pH 值和更低的预拔管 FiO，以及在出生后 6 小时内更低的“峰值”呼吸严重程度评分。
结论
我们使用了现成的人口统计学和临床数据来创建一个拔管准备估算器，为个体早产儿提供拔管成功的概率（http://elasticbeanstalk-us-east-2-676799334712.s3-website.us-east-2.amazonaws.com/）。
Zotero 插件