Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Seattle Children's Hospital, University of Washington, Seattle, Washington.
J Med Virol. 2020 Jan;92(1):4-10. doi: 10.1002/jmv.25576. Epub 2019 Sep 3.
The 11th International Conference on Human Herpesviruses (HHV)-6A, -6B, and -7 was held in Quebec City, from 23 to 26 June 2019. It attracted 144 basic, translational, and clinical scientists from 20 countries. Important new information was presented regarding: the mechanisms of chromosomal integration for HHV-6A and -6B; the biology of inherited chromosomally integrated HHV-6A and -6B; animal models for, and animal viruses with similarities to, HHV-6A, -6B, and -7; established and possible disease associations, including provocative new information suggesting these viruses may be one trigger of Alzheimer's disease, and new treatment strategies. In this review, we summarize presentations that were of particular interest. The full text of the Abstracts cited in the manuscript is available in the online Supporting Information Materials.
第 11 届人类疱疹病毒(HHV)-6A、-6B 和 -7 国际会议于 2019 年 6 月 23 日至 26 日在魁北克市举行。它吸引了来自 20 个国家的 144 名基础、转化和临床科学家。会议就以下方面提出了重要的新信息:HHV-6A 和 -6B 染色体整合的机制;遗传性染色体整合的 HHV-6A 和 -6B 的生物学;HHV-6A、-6B 和 -7 的动物模型以及与这些病毒具有相似性的动物病毒;已确立的和可能的疾病关联,包括令人信服的新信息表明这些病毒可能是阿尔茨海默病的一个诱因,以及新的治疗策略。在这篇综述中,我们总结了特别有趣的演讲。本文引用的摘要全文可在在线支持材料中获得。