Department of Orthopaedics and Traumatology, Peking University People's Hospital, Beijing, China.
Orthop Surg. 2019 Aug;11(4):643-652. doi: 10.1111/os.12512.
To identify baseline factors relevant to functional outcomes and health-related quality of life in the elderly with intertrochanteric fractures.
For the present study, 168 patients with intertrochanteric fracture who were assigned to different treatments between January 2016 and December 2017 were retrospectively selected. Hip function was assessed by Harris hip score (HHS), and health-related quality of life was evaluated by Barthel index (BI) of activities of daily living (ADL) and EuroQol 5-dimensions (EQ-5D) score, respectively. Data were analyzed by t-test, ANOVA, Pearson's correlation, χ -test, and multivariate linear regression.
A total of 164 (97.6%) patients completed the follow-up, with an average follow-up time of 15.7 ± 6.9 months; 39 (23.8%) patients died during the follow-up period and 125 (76.2%) patients were eligible for the functional analysis. HHS at final follow-up of 125 patients was 71.8 ± 13.1, and the following were associated with hip functional recovery: age (-0.45, 95% confidence interval (CI) -0.73 to -0.18, P < 0.01), serum albumin (0.65, 95% CI 0.04 to 1.27, P < 0.05), and ADL at discharge (0.18, 95% CI 0.01 to 0.33, P < 0.05). The Barthel index at final follow up in this cohort was 80.2 ± 18.1, and multivariable linear regression analysis showed that age (-0.49, 95% CI -0.85 to -0.12; P < 0.05), ADL score at discharge (0.29, 95% CI 0.07 to 0.51; P < 0.05) and internal fixation (16.3, 95% CI 3.3 to 29.3; P < 0.05) were associated with ADL at final follow-up. EQ-5D at final follow-up was 0.74 ± 0.2, with which HHS (0.012, 95% CI 0.011 to 0.013; P < 0.01) was positively associated.
We identify several baseline factors associated with hip functional outcome, health utility, and ADL in the elderly after an intertrochanteric fracture, of which we could modify mutable factors to achieve better outcomes. These findings could help to inform treatment and functional prognosis.
确定与老年股骨转子间骨折患者功能结局和健康相关生活质量相关的基线因素。
本研究回顾性选择了 2016 年 1 月至 2017 年 12 月期间接受不同治疗的 168 例股骨转子间骨折患者。采用 Harris 髋关节评分(HHS)评估髋关节功能,采用日常生活活动(ADL)Barthel 指数和欧洲五维健康量表(EQ-5D)评分分别评估健康相关生活质量。采用 t 检验、方差分析、Pearson 相关分析、χ ²检验和多元线性回归分析数据。
共有 164 例(97.6%)患者完成了随访,平均随访时间为 15.7±6.9 个月;随访期间 39 例(23.8%)患者死亡,125 例(76.2%)患者可进行功能分析。125 例患者最终随访时的 HHS 为 71.8±13.1,与髋关节功能恢复相关的因素有:年龄(-0.45,95%置信区间(CI)-0.73 至-0.18,P <0.01)、血清白蛋白(0.65,95%CI 0.04 至 1.27,P <0.05)和出院时的 ADL(0.18,95%CI 0.01 至 0.33,P <0.05)。该队列的最终随访时 Barthel 指数为 80.2±18.1,多变量线性回归分析显示,年龄(-0.49,95%CI -0.85 至-0.12;P <0.05)、出院时的 ADL 评分(0.29,95%CI 0.07 至 0.51;P <0.05)和内固定(16.3,95%CI 3.3 至 29.3;P <0.05)与最终随访时的 ADL 相关。最终随访时的 EQ-5D 为 0.74±0.2,与 HHS(0.012,95%CI 0.011 至 0.013;P <0.01)呈正相关。
我们确定了一些与老年股骨转子间骨折患者髋关节功能结局、健康效用和日常生活活动相关的基线因素,其中我们可以改变可变因素以获得更好的结果。这些发现有助于提供治疗和功能预后信息。