Allergy Immunology Unit, Department of Paediatrics, Advances Paediatrics Centre, Post Graduate Institute of Medical Education and Research , Chandigarh , India.
Expert Rev Clin Immunol. 2019 Oct;15(10):1089-1104. doi: 10.1080/1744666X.2019.1659726. Epub 2019 Oct 1.
: Kawasaki disease (KD) is one of the commonest pediatric vasculitides and is associated with a significant risk of development of coronary artery abnormalities if left untreated. : In this review, we have highlighted the incomplete and unusual presentations of KD and also emphasize the controversies pertaining to 2D echocardiography in KD. A PubMed search was performed regarding diagnosis and unusual presentations of KD. : Diagnosis of KD is essentially clinical and based on recognition of typical clinical features that may appear sequentially and all signs and symptoms may not be present at one point of time. There is no confirmatory laboratory test for diagnosis of this condition. Further complicating the picture is the fact that incomplete and atypical forms KD may be seen in up to 50% patients. Although 2D echocardiography continues to be the preferred imaging modality for cardiac assessment in patients with KD, it has its limitations.
川崎病（KD）是最常见的儿科血管炎之一，如果不治疗，会导致冠状动脉异常的风险显著增加。在这篇综述中，我们强调了 KD 不典型和不完全的表现，并强调了 2D 超声心动图在 KD 中的争议。我们对 KD 的诊断和不典型表现进行了 PubMed 检索。KD 的诊断主要基于临床，基于对可能依次出现的典型临床特征的识别，并非所有的体征和症状都能在同一时间出现。目前还没有确诊该病的实验室检测方法。更复杂的是，多达 50%的患者可能出现不完全和非典型 KD 。尽管 2D 超声心动图仍然是 KD 患者心脏评估的首选影像学方法，但它也有其局限性。
