Krawietz W, Loracher C, Struck E, Schlimok G, Falk H
I. Medizinische Klinik, Ludwig-Maximilians-Universität München.
Z Kardiol. 1988 Jul;77(7):470-3.
This is a report of a 25-year-old patient with known aortic valve stenosis since early youth and hemophilia A, showing recurrent joint bleeding. Acute Streptococcus endocarditis induced aortic valve insufficiency resulting in cardiac failure. Aortic valve replacement was performed after substitution of factor VIII, during which intra- and postoperative bleeding was prolonged by pericardial adhesions. Heparin was administered during cardiopulmonary-bypass as usual, but usual postoperative cumarin therapy was not initiated due to prolonged PTT time. One year postoperatively, the patient was in an excellent condition and fully rehabilitated.
这是一份关于一名25岁患者的报告，该患者自幼患有主动脉瓣狭窄且患有甲型血友病，表现为反复关节出血。急性链球菌性心内膜炎导致主动脉瓣关闭不全，进而引发心力衰竭。在输注凝血因子VIII后进行了主动脉瓣置换术，术中及术后因心包粘连导致出血时间延长。体外循环期间像往常一样使用了肝素，但由于部分凝血活酶时间延长，未开始常规的术后香豆素治疗。术后一年，患者状况良好，已完全康复。
