Mosiĭchuk N M, Zorin N A, Chebanov K O, Mateĭ T V
Zh Vopr Neirokhir Im N N Burdenko. 1988 Sep-Oct(5):30-3.
The authors examined 30 patients with intracranial hypertension caused by brain tumor who received 1 g/kg mannitol for dehydration. It was found that dehydration improves the function of the brain in the stage of subcompensation but makes it worse in the stage of decompensation. This has an effect both on the patients' general condition and on the EEG. The response of the healthy hemisphere to the administration of mannitol differed significantly from that of the involved hemisphere. Indications were determined for prescribing dehydration therapy according to the clinical stage of intracranial hypertension.
作者对30例因脑肿瘤引起颅内高压并接受1g/kg甘露醇脱水治疗的患者进行了研究。结果发现,脱水在代偿不全阶段可改善脑功能,但在失代偿阶段则会使其恶化。这对患者的一般状况和脑电图均有影响。健康半球对甘露醇给药的反应与受累半球有显著差异。根据颅内高压的临床阶段确定了脱水治疗的指征。