KSO介导的苯并噻唑在水溶液中与醇的羟基烷基化反应。
KSO-Mediated Hydroxyalkylation of Benzothiazoles with Alcohols in Aqueous Solution.
作者信息
Xu Wen-Xiu, Dai Xiao-Qiang, Weng Jian-Quan
机构信息
College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, People's Republic of China.
出版信息
ACS Omega. 2019 Jun 28;4(6):11285-11292. doi: 10.1021/acsomega.9b01695. eCollection 2019 Jun 30.
Abstract
The KSO-mediated hydroxyalkylation of 2-benzothiazoles with aliphatic alcohols in aqueous solution was described. The mild and convenient protocol generated a series of hydroxyalkylated benzothiazoles in moderate to good yields. Besides, benzimidazole and ethers were also compatible in this reaction, leading to corresponding C2 ether-substituted heteroarenes.
摘要
描述了在水溶液中KSO介导的2-苯并噻唑与脂肪醇的羟烷基化反应。该温和且简便的方法以中等到良好的产率生成了一系列羟烷基化苯并噻唑。此外，苯并咪唑和醚在该反应中也具有相容性，从而生成相应的C2醚取代的杂芳烃。
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