School of Chemistry and Chemical Engineering, Tianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, Tianjin University of Technology, Tianjin, 300384, China.
School of Life Science and Biotechnology, Dalian University of Technology, No. 2 Linggong Road, Dalian 116024, China.
J Mater Chem B. 2019 Sep 11;7(35):5286-5290. doi: 10.1039/c9tb01248f.
A photodynamic aggregation-induced emissive (AIE) fluorophore, characterized by near-infrared (NIR) emission, was created based on a fluorescence resonance energy transfer (FRET) donor of appreciable NIR up-conversion nanoparticles (UCNPs) and acceptor of immense fluorescence emissive AIEgen. Hence, the entrapment of the FRET couple into an amphiphilic saponin-based nanoscaled self-assembly demonstrated appealing theranostic functions in producing immense fluorescence emission and cytotoxic reactive oxygen species (ROS).
基于上转换纳米粒子（UCNPs）作为可观的近红外（NIR）上转换荧光供体和具有巨大荧光发射的聚集诱导发光（AIE）生色团作为受体，设计了一种具有近红外（NIR）发射特性的光动力聚集诱导发光（AIE）荧光团。因此，将 FRET 对包埋在两亲性皂素基纳米级自组装体中，在产生巨大荧光发射和细胞毒性活性氧（ROS）方面表现出了有吸引力的治疗诊断功能。
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