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系统性红斑狼疮中的骨髓纤维化和全血细胞减少症

Myelofibrosis and pancytopenia in systemic lupus erythematosus.

作者信息

el Mouzan M I, Ahmad M A, al Fadel Saleh M, al Sohaibani M O, al Gindan Y M

机构信息

Department of Pediatrics, University Al Khobar, Saudi Arabia.

出版信息

Acta Haematol. 1988;80(4):219-21. doi: 10.1159/000205641.

DOI:10.1159/000205641
PMID:3146200
Abstract

A 13-year-old Saudi girl presented with severe clinical features of systemic lupus erythematosus of 3 months' duration. In addition to laboratory evidence of the disease, the patient was found to have pancytopenia and myelofibrosis. While pancytopenia was considerably improved by steroids, myelofibrosis was not reversed. The coexistence of myelofibrosis and pancytopenia in patients with systemic lupus erythematosus has been reported, but their possible causal relationship remains unresolved.

摘要

一名13岁的沙特女孩出现了持续3个月的系统性红斑狼疮的严重临床症状。除了该疾病的实验室证据外,该患者还被发现全血细胞减少和骨髓纤维化。虽然类固醇使全血细胞减少症有了显著改善,但骨髓纤维化并未逆转。系统性红斑狼疮患者中骨髓纤维化和全血细胞减少症并存的情况已有报道,但其可能的因果关系仍未解决。

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Myelofibrosis and pancytopenia in systemic lupus erythematosus.系统性红斑狼疮中的骨髓纤维化和全血细胞减少症
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引用本文的文献

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Lessons learned from bone marrow failure in systemic lupus erythematosus: Case reports and review of the literature.系统性红斑狼疮骨髓衰竭的经验教训:病例报告和文献复习。
Semin Arthritis Rheum. 2018 Aug;48(1):90-104. doi: 10.1016/j.semarthrit.2017.12.004. Epub 2017 Dec 8.
2
Autoimmune myelofibrosis and systemic lupus erythematosus in a middle-aged male presenting only with severe anemia: a case report.一名仅表现为严重贫血的中年男性患者的自身免疫性骨髓纤维化和系统性红斑狼疮:病例报告
Medicine (Baltimore). 2015 May;94(19):e741. doi: 10.1097/MD.0000000000000741.
3
Haematological manifestations of lupus.
狼疮的血液学表现。
Lupus Sci Med. 2015 Mar 3;2(1):e000078. doi: 10.1136/lupus-2014-000078. eCollection 2015.
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Bone marrow fibrosis as a feature of systemic lupus erythematosus: a case report and literature review.骨髓纤维化作为系统性红斑狼疮的一项特征:病例报告及文献综述
Springerplus. 2014 Jul 9;3:349. doi: 10.1186/2193-1801-3-349. eCollection 2014.