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腿部钙化性肌坏死:一种罕见病症。

Calcific Myonecrosis of the Leg: A Rare Entity.

机构信息

Department of Orthopaedics and Orthopaedic Oncology, University of Padova, 35128 Padova, Italy.

First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, 115 27 Athens, Greece.

出版信息

Medicina (Kaunas). 2019 Aug 28;55(9):542. doi: 10.3390/medicina55090542.

DOI:10.3390/medicina55090542
PMID:31466356
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6780786/
Abstract

Calcific myonecrosis is a rare disease that has been shown to be a late sequela of trauma. This article presents a 68-year-old man with calcific myonecrosis of the leg 40 years after a tibial fracture complicated with peroneal nerve palsy. The soft tissue mass increased in size after another injury to the leg that occurred two years before his presentation. Physical examination at presentation showed a palpable extra-osseous mass at the anterior aspect of the left leg; the mass was not adherent to adjacent soft-tissues and bone, and it was painless but tender to palpation. Radiographs of the left leg showed extensive calcification at the soft-tissue of the anterior and posterior leg. An ultrasonography-guided trocar biopsy was done; histological findings were indicative of calcific myonecrosis. Given the benign entity of the lesion and known high rate of complications, he was recommended for no further treatment except for clinical and imaging observation. Located at the site of the biopsy, he experienced infection with drainage that eventually healed after six months with antibiotics and wound dressing changes. During the last follow-up examination, two years after diagnosis, the patient was asymptomatic without progression of the mass.

摘要

钙化性肌炎是一种罕见疾病,已被证实是创伤的晚期后遗症。本文报告了一例 68 岁男性患者,在胫骨骨折合并腓总神经麻痹 40 年后出现腿部钙化性肌炎。在他就诊前两年,腿部再次受伤后,软组织肿块增大。就诊时体格检查显示左小腿前侧可触及到一个可触及的骨外肿块;肿块与邻近的软组织和骨骼无粘连,无触痛,但压痛。左小腿的 X 线片显示小腿前后软组织广泛钙化。进行了超声引导下的穿刺活检;组织学检查结果提示为钙化性肌炎。鉴于病变的良性性质和已知的高并发症发生率,除了临床和影像学观察外,不建议进一步治疗。在活检部位,他经历了感染并引流,最终在六个月的抗生素和伤口换药治疗后愈合。在诊断后两年的最后一次随访检查中,患者无症状,肿块无进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79be/6780786/324792c11a01/medicina-55-00542-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79be/6780786/6497ab5f02ed/medicina-55-00542-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79be/6780786/c1f8bca9bb8f/medicina-55-00542-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79be/6780786/324792c11a01/medicina-55-00542-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79be/6780786/6497ab5f02ed/medicina-55-00542-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79be/6780786/c1f8bca9bb8f/medicina-55-00542-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79be/6780786/324792c11a01/medicina-55-00542-g003.jpg

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Oncol Lett. 2018 May;15(5):7909-7913. doi: 10.3892/ol.2018.8320. Epub 2018 Mar 22.
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Calcific myonecrosis following snake bite: a case report and review of the literature.蛇咬伤后钙化性肌坏死:一例病例报告及文献综述
J Med Case Rep. 2014 Jun 16;8:193. doi: 10.1186/1752-1947-8-193.
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Bilateral calcific myonecrosis associated with epilepsy.双侧钙化性肌坏死与癫痫相关。
World J Clin Cases. 2022 Mar 26;10(9):2901-2907. doi: 10.12998/wjcc.v10.i9.2901.
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Tabetic arthropathy of the knee, complicated by lower limb myonecrosis.膝关节脊髓痨性关节病,并发下肢肌坏死。
BMJ Case Rep. 2021 Jul 19;14(7):e242753. doi: 10.1136/bcr-2021-242753.
Clin Radiol. 2013 Jun;68(6):e349-52. doi: 10.1016/j.crad.2012.12.001. Epub 2013 Mar 26.
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[Calcific myonecrosis of the leg].[腿部钙化性肌坏死]
Rev Esp Cir Ortop Traumatol. 2012 Jan-Feb;56(1):46-50. doi: 10.1016/j.recot.2011.07.009. Epub 2011 Sep 17.
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Calcific myonecrosis: a case report and review of the literature.钙化性肌坏死:一例病例报告及文献综述
BMJ Case Rep. 2012 Oct 10;2012:bcr2012007186. doi: 10.1136/bcr-2012-007186.
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Calcific myonecrosis: a two-patient case series.钙化性肌坏死:两例病例报告。
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Calcific myonecrosis of the upper extremity: case report.上肢钙化性肌坏死:病例报告
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Calcific myonecrosis of the leg: report of three patients presenting with infection.腿部钙化性肌坏死:三例以感染为表现的患者报告。
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