Korivi Mallikarjuna, Chen Chun-Tai, Yu Szu-Hsien, Ye Weibing, Cheng I-Shiung, Chang Jhong-Sin, Kuo Chia-Hua, Hou Chien-Wen
Exercise and Metabolism Research Center, College of Physical Education and Health Sciences, Zhejiang Normal University, Jinhua 321004, China.
Laboratory of Exercise Biochemistry, Institute of Sports Sciences, University of Taipei, Taipei 11153, Taiwan.
Evid Based Complement Alternat Med. 2019 Jul 28;2019:3528932. doi: 10.1155/2019/3528932. eCollection 2019.
We investigated the effect of chronic seaweed () supplementation on maximal carrying capacity, muscle mass, and oxidative stress in rats following high-intensity resistance exercise (RE). Forty Sprague-Daley rats were equally categorized into control, exercise, seaweed, and exercise plus seaweed (ES) groups. Rats in respective groups performed RE (once per 2 days) or received seaweed (250 mg/kg bodyweight, orally) for 10 weeks. Results showed that seaweed consumption in combination with RE significantly ( < 0.05) increased maximal weight carrying capacity compared to RE alone. FHL muscle mass was significantly higher in both exercise and ES groups. Notably, high-intensity RE-induced lipid peroxidation, as evidenced by elevated thiobarbituric acid reactive substances (TBARS) in muscle, was substantially diminished ( < 0.05) by seaweed treatment. This antioxidative effect of seaweed was further represented by augmented superoxide dismutase activity and glutathione levels in seaweed groups. We noticed increased insulin concentrations and HOMA-IR, while the fasting blood glucose levels remained stable in seaweed and ES groups. Our findings conclude that seaweed in combination with RE enhanced maximal carrying strength and attenuated oxidative stress through improved antioxidant capacity. Seaweed could be a potential nutritional supplement to boost performance and to prevent exercise-induced muscle damage.
我们研究了长期补充海藻对高强度抗阻运动（RE）后大鼠的最大承载能力、肌肉质量和氧化应激的影响。40只斯普拉格-戴利大鼠被平均分为对照组、运动组、海藻组和运动加海藻（ES）组。各组大鼠进行抗阻运动（每2天1次）或接受海藻（250毫克/千克体重，口服），持续10周。结果显示，与单独进行抗阻运动相比，海藻与抗阻运动联合使用显著（P<0.05）提高了最大负重能力。运动组和ES组的FHL肌肉质量均显著更高。值得注意的是，高强度抗阻运动诱导的脂质过氧化，表现为肌肉中硫代巴比妥酸反应性物质（TBARS）升高，通过海藻处理得到了显著减轻（P<0.05）。海藻组超氧化物歧化酶活性增强和谷胱甘肽水平升高进一步体现了海藻的这种抗氧化作用。我们注意到海藻组和ES组的胰岛素浓度和HOMA-IR升高，而空腹血糖水平保持稳定。我们的研究结果表明，海藻与抗阻运动联合使用可通过提高抗氧化能力增强最大承载强度并减轻氧化应激。海藻可能是一种潜在的营养补充剂，可提高运动表现并预防运动诱导的肌肉损伤。
