Palatroni P, Gabrielli M G, Grappasonni I
Department of Cellular Biology, University of Camerino, Italy.
Acta Histochem. 1988;84(1):1-14. doi: 10.1016/S0065-1281(88)80003-5.
Histochemical, biochemical, and histophotometrical studies of carbonic anhydrase activity have been carried out on the stomach of the various vertebrate classes, in order to make functional comparisons. Our results on carbonic anhydrase activity of epithelial surface may be interpreted in favour of a protective role by the secretion of an alkaline fluid against damage due to intraluminal low pH values. As regards the presence of carbonic anhydrase in the different types of gastric glandular cells, in addition to the already known function of the enzyme in hydrochloric acid secretion in the oxyntic and oxyntic-peptic cells, we suggest an interpretation of carbonic anhydrase presence observed in many chief cells.
为了进行功能比较，已对各类脊椎动物的胃进行了碳酸酐酶活性的组织化学、生物化学和组织光度学研究。我们关于上皮表面碳酸酐酶活性的研究结果，可能支持通过分泌碱性液体来保护胃免受腔内低pH值造成损伤的观点。至于不同类型胃腺细胞中碳酸酐酶的存在情况，除了该酶在壁细胞和壁-主细胞分泌盐酸中的已知功能外，我们还对在许多主细胞中观察到的碳酸酐酶的存在情况提出了一种解释。
