Xiaolan Xie, Wujie Guan, Xiaoyan Tang, Wenlai Chang
Nursing Department, Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine Hospital, Nanhai, Guangdong, China.
Endocrine Department, Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine Hospital, Nanhai, Guangdong, China.
J Int Med Res. 2019 Oct;47(10):4656-4663. doi: 10.1177/0300060519858033. Epub 2019 Aug 30.
This study aimed to examine the effects of ultrasonic debridement plus a wet dressing of Shenghong (SH) on chronic ulcer healing of the lower extremities in patients with diabetes.
Sixty cases of diabetes combined with chronic lower limb ulcers were randomly divided into control (n = 30) and experimental (n = 30) groups. The control group was treated with ultrasonic debridement plus recombinant human fibroblast growth factor (FGF) gel. The experimental group was treated with ultrasonic debridement plus SH wet dressing.
The mean clinical efficacy in the experimental group was significantly higher than that in the control group (93.33% ± 6.32% versus 60.0% ± 5.87%). The mean ulcer area was significantly smaller and the mean ulcer healing rate was significantly shorter in the first 3 months, and the mean overall pain intensity score was significantly lower in the experimental group than in the control group. Moreover, the positive rates of bacterial culture on the 7 and 15 days were significantly lower in the experimental group than in the control group.
The use of ultrasonic debridement plus SH wet dressing for treating ulcers can significantly improve clinical efficacy and promote healing.
本研究旨在探讨超声清创联合生肌(SH)湿敷对糖尿病患者下肢慢性溃疡愈合的影响。
将60例糖尿病合并下肢慢性溃疡患者随机分为对照组(n = 30)和实验组(n = 30)。对照组采用超声清创联合重组人成纤维细胞生长因子(FGF)凝胶治疗。实验组采用超声清创联合SH湿敷治疗。
实验组的平均临床疗效显著高于对照组(93.33% ± 6.32% 对 60.0% ± 5.87%)。在最初3个月,实验组的平均溃疡面积显著更小,平均溃疡愈合时间显著更短,且实验组的平均总体疼痛强度评分显著低于对照组。此外,实验组在第7天和第15天的细菌培养阳性率显著低于对照组。
采用超声清创联合SH湿敷治疗溃疡可显著提高临床疗效并促进愈合。