State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong, China; New England College of Optometry, Boston, Massachusetts, USA.
Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, China.
J Cataract Refract Surg. 2019 Sep;45(9):1340-1345. doi: 10.1016/j.jcrs.2019.03.030.
This meta-analysis studied toric intraocular lens (IOL) alignment accuracy using image-guided and manual marking methods by comparing the axis misalignment of toric IOLs, percentage of eyes with toric IOL axis misalignment within ±5 degrees, postoperative astigmatism, difference vector, and postoperative uncorrected distance visual acuity. The methodological quality was assessed using the modified Quality Assessment of Diagnostic Accuracy Studies-2 tool. Continuous variables were analyzed using weighted mean differences, and dichotomous variables were compared using the odds ratio. Five studies comprising a total of 257 eyes were analyzed. For heterogeneity, neither sensitivity analysis nor the Egger test detected statistical findings. The image-guided marking group had smaller toric IOL axis misalignment (P < .00001), less postoperative astigmatism (P = .003), and a smaller difference vector (P < .00001) than the manual marking group. The overall evidence from the studies indicates that image-guided marking is better than manual marking, resulting in less axis misalignment, a smaller difference vector, and less postoperative astigmatism.
本荟萃分析通过比较使用图像引导和手动标记方法的散光人工晶状体（IOL）的定位准确性，研究了散光 IOL 轴位的偏差、轴位偏差在±5 度以内的眼的百分比、术后散光、差异向量和术后未矫正的距离视力。使用改良的诊断准确性研究-2 工具评估方法学质量。连续变量采用加权均数差进行分析，二分类变量采用比值比进行比较。对 5 项共 257 只眼的研究进行了分析。敏感性分析和 Egger 检验均未检测到异质性的统计学结果。与手动标记组相比，图像引导标记组的散光 IOL 轴位偏差更小（P <.00001），术后散光更小（P =.003），差异向量更小（P <.00001）。研究的总体证据表明，图像引导标记优于手动标记，导致轴位偏差更小、差异向量更小、术后散光更小。
