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前瞻性研究比较完全和不完全下肢静脉双功能超声检查深静脉血栓形成的发生率。

Prospective study comparing the rate of deep venous thrombosis of complete and incomplete lower extremity venous duplex ultrasound examinations.

机构信息

Department of Vascular Surgery, School of Medicine, Oregon Health & Science University, Portland, Ore.

Department of Vascular Surgery, School of Medicine, Oregon Health & Science University, Portland, Ore.

出版信息

J Vasc Surg Venous Lymphat Disord. 2019 Nov;7(6):882-888. doi: 10.1016/j.jvsv.2019.05.014. Epub 2019 Aug 27.

Abstract

BACKGROUND

A lower extremity venous duplex ultrasound (LEVDUS) examination positive for deep venous thrombosis (DVT) is an indication for anticoagulation. Incomplete examinations that fail to examine all lower extremity veins in patients not otherwise indicated for anticoagulation may be followed by repeated examination to exclude missed or progressing DVT. This study examined the frequency of incomplete LEVDUS studies, reasons for incomplete studies, veins incompletely examined, and follow-up LEVDUS after incomplete LEVDUS. The incidence of a positive finding of DVT was compared between initial complete LEVDUS and follow-up LEVDUS after an initial incomplete examination to determine whether improving rates of follow-up LEVDUS after an incomplete examination is a reasonable target for quality improvement.

METHODS

At a single academic medical center from January 2017 to December 2017, incomplete LEVDUS studies were prospectively identified in patients who did not otherwise have an identified indication for anticoagulation. Rate of DVT in complete LEVDUS was also determined during the same time frame. Incomplete LEVDUS reports were reviewed for clinical setting, patient demographics, examination indication, ordering providers, reasons for incomplete examinations, anatomic locations of veins not visualized, rates of follow-up LEVDUS examinations within 30 days of the initially incomplete study, and rates of DVT identified in follow-up examinations of initially incomplete examinations.

RESULTS

Of the 2843 LEVDUS examinations performed in 2017, 341 studies identified DVT and 197 incomplete examinations did not identify DVT. Veins not visualized on incomplete studies included tibial veins (n = 170 [86.3%]), femoral veins (n = 73 [37.1%]), and popliteal veins (n = 76 [38.6%]), with the most common reasons for incomplete studies being bandages or fixation devices (46.2%), intolerance of the patient for the study (14.7%), and body habitus or edema (17.4%). Only a minority of incomplete studies not identifying DVT (27.9%) had a follow-up examination performed. The majority of the repeated examinations were performed after incomplete LEVDUS examinations that were originally performed for high-risk screening (80%) as opposed to clinical suspicion for DVT (20%). There was no significant difference in demographic features of patients with initially incomplete studies who did or did not have a follow-up examination and no significant difference in the rates of DVT (13.1%) in complete LEVDUS examinations compared with the rate of DVT found in follow-up examinations of initially incomplete LEVDUS examinations (9.1%; P = .33).

CONCLUSIONS

The majority of patients with incomplete LEVDUS, even those with symptoms or signs suggestive of DVT, do not have a follow-up examination within 30 days of the incomplete study. The rate of DVT detected in initially complete studies was similar to that in patients with follow-up examinations whose initial study was incomplete and did not identify DVT. This suggests that to avoid missing DVT in patients with incomplete LEVDUS studies, quality assurance programs should be initiated to ensure that follow-up LEVDUS studies are performed after an incomplete LEVDUS examination.

摘要

背景

下肢静脉双功能超声(LEVDUS)检查提示深静脉血栓形成(DVT)阳性是抗凝治疗的指征。对于未明确抗凝指征的患者,未检查所有下肢静脉的不完整检查可能会重复进行,以排除遗漏或进展性 DVT。本研究检查了不完整 LEVDUS 检查的频率、不完整检查的原因、未检查的静脉以及不完整 LEVDUS 后的随访 LEVDUS。比较了初始完整 LEVDUS 和初始不完整检查后的随访 LEVDUS 中 DVT 的阳性发现率,以确定提高不完整检查后随访 LEVDUS 的比例是否是质量改进的合理目标。

方法

在 2017 年 1 月至 12 月期间,在一家学术医疗中心对未明确抗凝指征的患者进行了前瞻性识别不完整 LEVDUS 检查。同时还确定了在同一时间段内完整 LEVDUS 检查中 DVT 的发生率。对不完整 LEVDUS 报告进行了检查,以了解临床环境、患者人口统计学、检查指征、开单医生、不完整检查的原因、未显影静脉的解剖部位、初始不完整检查后 30 天内进行随访 LEVDUS 检查的比例以及初始不完整检查后随访检查中发现 DVT 的比例。

结果

在 2017 年进行的 2843 次 LEVDUS 检查中,341 次检查发现 DVT,197 次不完整检查未发现 DVT。不完整检查未显影的静脉包括胫骨静脉(n=170 [86.3%])、股静脉(n=73 [37.1%])和腘静脉(n=76 [38.6%]),不完整检查的最常见原因是绷带或固定装置(46.2%)、患者不耐受检查(14.7%)和体型或水肿(17.4%)。只有少数不完整检查未发现 DVT(27.9%)进行了随访检查。大多数重复检查是在最初为高危筛查(80%)而不是出于对 DVT 的临床怀疑(20%)进行的不完整 LEVDUS 检查后进行的。未进行随访检查的初始不完整研究患者与进行了随访检查的患者在人口统计学特征方面没有显著差异,且在完整 LEVDUS 检查中发现 DVT 的比例(13.1%)与初始不完整 LEVDUS 检查的随访检查中发现 DVT 的比例(9.1%)也没有显著差异(P=0.33)。

结论

大多数不完整 LEVDUS 检查的患者,即使有 DVT 的症状或体征,也不会在不完整检查后的 30 天内进行随访检查。在初始完整研究中发现 DVT 的比例与初始不完整 LEVDUS 检查未发现 DVT 但进行了随访检查的患者相似。这表明,为避免在不完整 LEVDUS 检查的患者中漏诊 DVT,应启动质量保证计划,以确保在不完整 LEVDUS 检查后进行随访 LEVDUS 检查。

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