The Jules Stein Eye Institute, University of California, Los Angeles, CA, USA.
The Doheny Eye Institute, University of California, Los Angeles, CA, USA.
Eye (Lond). 2020 Apr;34(4):663-668. doi: 10.1038/s41433-019-0565-1. Epub 2019 Aug 30.
To report a case series of 14 patients presenting with facial numbness primarily to the ophthalmology clinic.
All patients presenting with facial numbness to the ophthalmology clinic at the University of California, Los Angeles, were reviewed for study entry between 1993 and the present. Patients with a history of trauma or surgery were excluded.
Fourteen patients (eight females and six males) presented to the ophthalmology clinic with numbness. Nine patients (64%) presented primarily with numbness. This symptom was associated with mortality (57%) and significant morbidity. The most common cause was neoplastic pathology (n = 10, 71%), with perineural spread from squamous cell carcinoma being the most common (five cases, 36%). The remaining cases were related to infection (n = 4, 29%).
Most of the patients presenting to our service with numbness eventually died due to their condition. Given the poor prognosis of the patients in our case series, numbness of the face may be a portentous sign and therefore warrants a thorough examination with close follow up.
报告 14 例以面部麻木为主要表现首诊于眼科门诊的患者病例系列。
1993 年至目前，我们对所有因面部麻木首诊于加利福尼亚大学洛杉矶分校眼科门诊的患者进行了研究入选回顾。排除有外伤或手术史的患者。
14 例患者（8 名女性和 6 名男性）因麻木就诊于眼科门诊。9 例（64%）患者主要表现为麻木。该症状与死亡率（57%）和显著发病率相关。最常见的病因是肿瘤性病变（n=10，71%），最常见的是鳞状细胞癌的神经周围播散（5 例，36%）。其余病例与感染有关（n=4，29%）。
我们的服务中大多数因麻木就诊的患者最终因病情而死亡。鉴于我们的病例系列中患者的预后较差，面部麻木可能是一个不祥的征兆，因此需要进行彻底的检查和密切随访。
