Department of Radiology, Korea University Anam Hospital, Korea University College of Medicine, 73, Goryeodae-ro, Seongbuk-gu, Seoul, 02841, Korea.
Abdom Radiol (NY). 2019 Dec;44(12):4037-4047. doi: 10.1007/s00261-019-02202-0.
To compare the effects of gadoxetic acid and gadoteric acid on the image quality of single-breath-hold, triple (first, second, and third) arterial hepatic magnetic resonance imaging (MRI).
Two hundred and eleven patients were divided into two groups according to the contrast materials used (gadoxetic acid, 108 patients and gadoteric acid, 103 patients). All 3.0-T MR examinations included triple arterial phase acquisition using the 4D enhanced T1-weighted high-resolution isotropic volume examination (eTHRIVE) keyhole technique. The image qualities of the pre-contrast and triple arterial phases were assessed in terms of image artifacts, sharpness of the intrahepatic vessel and liver edge, and overall image quality with a 5-point scale for qualitative analysis.
The image quality of gadoxetic acid-enhanced liver MRI in the triple arterial phases was significantly degraded compared with that of gadoteric acid-enhanced liver MRI, although better image scores were observed in the pre-contrast images in the gadoxetic acid group (P < 0.001). The overall image quality gradually improved from the first to the third arterial phases in both groups (P < 0.003).
Intravenous gadoxetic acid could have a detrimental effect on image quality of triple arterial phase MRI with the 4D eTHRIVE Keyhole technique. The third arterial phase images had the best image qualities; thus, they could be used as key scans.
比较钆塞酸二钠和钆特酸二钠对单次屏气、三（第 1、2、3 期）动脉期肝脏磁共振成像（MRI）图像质量的影响。
根据使用的对比剂（钆塞酸二钠 108 例，钆特酸二钠 103 例）将 211 例患者分为两组。所有 3.0-T MR 检查均采用 4D 增强 T1 加权高分辨率各向同性容积检查（eTHRIVE）钥匙孔技术进行三期动脉期采集。在定性分析中，使用 5 分制评估对比前和三期动脉期的图像伪影、肝内血管和肝缘锐利度以及整体图像质量。
尽管钆塞酸二钠组的对比前图像评分更好（P<0.001），但与钆特酸二钠增强肝 MRI 相比，钆塞酸二钠增强肝 MRI 的三期动脉期图像质量明显下降。两组的整体图像质量均从第一期动脉期逐渐提高到第三期动脉期（P<0.003）。
静脉注射钆塞酸二钠可能会对使用 4D eTHRIVE 钥匙孔技术的三期动脉期 MRI 图像质量产生不利影响。第三期动脉期图像质量最佳，因此可作为关键扫描。
