Servicio de Dermatología, Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria la Princesa (IIS-IP), Madrid, España.
Servicio de Dermatología, Hospital de Bellvitge, Barcelona, España.
Actas Dermosifiliogr (Engl Ed). 2020 Mar;111(2):143-148. doi: 10.1016/j.ad.2019.07.002. Epub 2019 Aug 28.
Body surface area (BSA) affected by psoriasis is one of the most often used measures for assessing severity, but this method has shortcomings.
To validate a new way to estimate BSA.
Prospective, multicenter study in 56 patients with psoriasis. Each patient was evaluated by 2 dermatologists in 2 visits to the same hospital. Each dermatologist used 2 methods for estimating BSA: the traditional visual estimation in which the area of the palm equals 1% of the total body surface and an optical pencil (OP) method in which the affected area is drawn on a touch screen. Software in the application then calculates the BSA.
Overall concordance between the 2 methods was acceptable according to an intraclass correlation coefficient (ICC) of 0.87. However, the limits of agreement were unacceptably large and there was systematic bias: traditional estimates were consistently greater than OP calculations. Concordance between the methods was better (ICC>0.8) on the trunk and lower extremities. Intraobserver reliability was excellent with both methods (ICCs, 0.97 and 0.98 for the traditional and OP estimates, respectively). Interobserver reliability was also high (ICCs, 0.91 and 0.94 for the traditional and OP methods), although the mean BSA differed significantly between observers. The ICCs were much lower for BSA estimates on the head.
This study to validate the OP method for estimating the affected BSA in patients with psoriasis shows good agreement between the OP and traditional approaches. The OP calculations also showed less variance and better interobserver reliability.
受银屑病影响的体表面积(BSA)是评估疾病严重程度最常用的指标之一,但这种方法存在缺陷。
验证一种新的 BSA 估计方法。
对 56 例银屑病患者进行前瞻性、多中心研究。每位患者由 2 位皮肤科医生在同一家医院的 2 次就诊中进行评估。每位皮肤科医生使用 2 种方法估计 BSA:传统的视觉估计法,其中手掌面积等于全身表面积的 1%;光学铅笔(OP)法,即受影响的区域在触摸屏上绘制。应用程序中的软件随后计算 BSA。
根据 ICC 为 0.87,两种方法之间的总体一致性可接受。然而,一致性界限范围过大,且存在系统偏差:传统估计值始终大于 OP 计算值。两种方法在躯干和下肢的一致性更好(ICC>0.8)。两种方法的观察者内可靠性均极佳(ICC 分别为 0.97 和 0.98)。观察者间可靠性也很高(ICC 分别为 0.91 和 0.94),尽管观察者之间的平均 BSA 差异显著。对于头部的 BSA 估计,ICC 要低得多。
这项验证 OP 法估计银屑病患者受累 BSA 的研究表明,OP 法与传统方法之间具有良好的一致性。OP 计算还显示出更小的变异性和更好的观察者间可靠性。