Dzhanpoladian E G, Karagezian K G, Sambelian V M, Aloian G A
Kardiologiia. 1988 Oct;28(10):88-90.
Antianginal treatment of animals with experimentally induced myocardial ischemia produced significant effects on the quantitative and qualitative composition of phospholipids: total phospholipids returned to normal levels, cardiolipins and phosphatidilinosytes were drastically increased. In ischemia, this lipid metabolism derangement appears to be of great significance as it enables the physiochemical status of biological membranes to be relatively stabilized, which is an essential condition for the enzymic system of cardiomyocytes to act.
对实验性诱导心肌缺血的动物进行抗心绞痛治疗，对磷脂的定量和定性组成产生了显著影响：总磷脂恢复到正常水平，心磷脂和磷脂酰肌醇大幅增加。在缺血状态下，这种脂质代谢紊乱似乎具有重要意义，因为它能使生物膜的物理化学状态相对稳定，这是心肌细胞酶系统发挥作用的必要条件。
