Dababneh Reem, Al-Kaisi Nabih, Haddad Noor, Al Khouri Zaid, Bissada Nabil F
King Hussein Medical Center - Royal Medical Services; Amman, Jordan.
School of Dental Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
J Int Acad Periodontol. 2017 Apr 1;19(2):65-68.
A case of localized soft tissue growth located on the lingual aspect of the left mandibular gingiva is reported in a 61-year-old male patient in whom excisional biopsy of the lesion was performed. The histopathologic diagnosis was adenocarcinoma. Further clinical and biopsy examinations taken from several organs indicated the presence of metastatic adenocarcinomas in the brain, spleen, lymph nodes, and liver. The oral tumor recurred after repeated surgical removal. Based on histopathological examination and immunoprofiling analysis the primary tumor probably originated in the gastrointestinal tract.
报告了一例61岁男性患者，其左下颌牙龈舌侧出现局限性软组织肿物，并对该病变进行了切除活检。组织病理学诊断为腺癌。对多个器官进行的进一步临床检查和活检显示，脑、脾、淋巴结和肝脏存在转移性腺癌。经反复手术切除后，口腔肿瘤复发。根据组织病理学检查和免疫表型分析，原发性肿瘤可能起源于胃肠道。
